Genome Sequence of Aedes aegypti, a Major Arbovirus Vector
We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …
Construction and characterization of a normalized cDNA library.
MB Soares, MF Bonaldo, P Jelene… - Proceedings of the …, 1994 - National Acad Sciences
We have developed a simple procedure based on reassociation kinetics that can reduce
effectively the high variation in abundance among the clones of a cDNA library that represent …
effectively the high variation in abundance among the clones of a cDNA library that represent …
[HTML][HTML] The P4 health spectrum–a predictive, preventive, personalized and participatory continuum for promoting healthspan
…, BS McEwen, MB Soares… - Progress in …, 2017 - journals.lww.com
Chronic diseases (ie, noncommunicable diseases), mainly cardiovascular disease, cancer,
respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and …
respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and …
[HTML][HTML] Insights into a dinoflagellate genome through expressed sequence tag analysis
Background Dinoflagellates are important marine primary producers and grazers and cause
toxic "red tides". These taxa are characterized by many unique features such as immense …
toxic "red tides". These taxa are characterized by many unique features such as immense …
[HTML][HTML] Identification of differentially expressed microRNAs in osteosarcoma
…, PM Chou, MF Bonaldo, EF Vanin, MB Soares - Sarcoma, 2011 - hindawi.com
A limited number of reports have investigated the role of microRNAs in osteosarcoma. In this
study, we performed miRNA expression profiling of osteosarcoma cell lines, tumor samples, …
study, we performed miRNA expression profiling of osteosarcoma cell lines, tumor samples, …
[HTML][HTML] Identification of microRNAs as potential prognostic markers in ependymoma
…, D Wang, S Goldman, T Tomita, MB Soares - PloS one, 2011 - journals.plos.org
Introduction We have examined expression of microRNAs (miRNAs) in ependymomas to
identify molecular markers of value for clinical management. miRNAs are non-coding RNAs …
identify molecular markers of value for clinical management. miRNAs are non-coding RNAs …
Genome-wide quantitative assessment of variation in DNA methylation patterns
…, S Goldman, T Tomita, MB Soares - Nucleic acids …, 2011 - academic.oup.com
Genomic DNA methylation contributes substantively to transcriptional regulations that
underlie mammalian development and cellular differentiation. Much effort has been made to …
underlie mammalian development and cellular differentiation. Much effort has been made to …
[HTML][HTML] Folic acid remodels chromatin on Hes1 and Neurog2 promoters during caudal neural tube development
…, DG McLone, T Tomita, MB Soares… - Journal of Biological …, 2010 - ASBMB
The mechanism(s) behind folate rescue of neural tube closure are not well understood. In
this study we show that maternal intake of folate prior to conception reverses the proliferation …
this study we show that maternal intake of folate prior to conception reverses the proliferation …
Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus
The ventromedial hypothalamic nucleus (VMH) plays an important role in the control of feeding
and energy homeostasis. In contrast to other hypothalamic nuclei that are also known to …
and energy homeostasis. In contrast to other hypothalamic nuclei that are also known to …
High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum
…, S Goldman, T Tomita, MB Soares - Nucleic acids …, 2009 - academic.oup.com
DNA methylation, the only known covalent modification of mammalian DNA, occurs primarily
in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% …
in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% …