Introduction Inherited variability in host immune responses influences susceptibility and
outcome of Influenza A virus (IAV) infection, but these factors remain largely unknown. …

Objective. To determine the incidence of pneumonia and associated factors in a single-center
systemic lupus erythematosus (SLE) cohort. Methods. We included all our SLE patients […

Background Typhoid fever, caused by the intracellular pathogen Salmonella (S.) enterica
serovar Typhi, remains a major cause of morbidity and mortality worldwide. Granzymes are …

We conducted a nationwide surveillance of the variable 5′ emm-like (M-like protein gene)
sequences from 214 pharyngeal group C and group G streptococci. Almost 75% of the …

… Mª Isabel García Laorden, bajo mi dirección y asesoramiento, considerando que es apto
para su defensa ante tribunal y reune las condiciones exigibles para optar al grado de doctor. …

We report a series of 14 patients from 11 kindreds with recessive partial (RP)-interferon (IFN)-γR1
deficiency. The I87T mutation was found in nine homozygous patients from Chile, …

Background Acute respiratory distress syndrome (ARDS) is a lung inflammatory process
caused mainly by sepsis. Most previous studies that identified genetic risks for ARDS focused …

Streptococcus pyogenes, or group A Streptococcus, is one of the most frequent causes of
pharyngitis and skin infections in humans. Many virulence mechanisms have been suggested …

The acute respiratory distress syndrome (ARDS) is an acute inflammatory process of the lung
caused by a direct or indirect insult to the alveolar-capillary membrane. Currently, ARDS is …

Objective: To assess the potential association of the functional polymorphism rs1801274 in
the receptor IIa for the Fc portion of immunoglobin G (FcγRIIa) gene (FCGR2A-H131R) with …