A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function

K Okunishi, M Dohi, K Nakagome… - The Journal of …, 2005 - journals.aai.org
Hepatocyte growth factor (HGF) plays an important role in many biological events such as
angiogenesis, cell proliferation, anti-fibrosis and antiapoptosis. It is well known that HGF …

Consensus statement for the diagnosis and treatment of drug-induced lung injuries.

…, F Sakai, Y Sugiyama, K Tatsumi, M Dohi… - Respiratory …, 2013 - europepmc.org
Consensus statement for the diagnosis and treatment of drug-induced lung injuries. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu …

In vivo IL-10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF-β in the lung

K Nakagome, M Dohi, K Okunishi, R Tanaka… - Thorax, 2006 - thorax.bmj.com
Backgroud: Idiopathic pulmonary fibrosis is a devastating disorder for which there is no
effective treatment. Transforming growth factor (TGF)-β plays a critical role in provoking fibrosis. …

Hepatocyte growth factor attenuates collagen accumulation in a murine model of pulmonary fibrosis

M Dohi, T Hasegawa, K Yamamoto… - American journal of …, 2000 - atsjournals.org
We investigated the in vivo effects of recombinant human hepatocyte growth factor (HGF) on
epithelial cell proliferation in normal mouse lung and on the repair process that follows …

Hepatocyte growth factor significantly suppresses collagen-induced arthritis in mice

K Okunishi, M Dohi, K Fujio, K Nakagome… - The Journal of …, 2007 - journals.aai.org
Hepatocyte growth factor (HGF) plays an important role in angiogenesis, cell proliferation,
antifibrosis, and antiapoptosis. Moreover, recent studies have highlighted the …

[HTML][HTML] Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy

T Ishii, K Doi, K Okamoto, M Imamura, M Dohi… - The American journal of …, 2010 - Elsevier
Acute kidney injury (AKI) is a serious problem in critically ill patients of intensive care units. It
has been reported previously that AKI can induce acute lung injury (ALI), as well as cause …

Dopamine D1-like receptor antagonist attenuates Th17-mediated immune response and ovalbumin antigen-induced neutrophilic airway inflammation

…, K Hagiwara, M Kanazawa, M Dohi… - The Journal of …, 2011 - journals.aai.org
Allergic airway inflammation is generally considered a Th2-type immune response. Recent
studies, however, demonstrated that Th17-type immune responses also play important roles …

Clinical and radiological features of Pneumocystis pneumonia in patients with rheumatoid arthritis, in comparison with methotrexate pneumonitis and Pneumocystis …

…, H Yamada, T Johkoh, A Imamura, M Dohi… - Internal …, 2008 - jstage.jst.go.jp
Objective To elucidate the clinical and radiological features of Pneumocystis pneumonia (PCP)
in patients with rheumatoid arthritis (RA), compared with methotrexate (MTX) …

High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10–associated mechanism

…, J Miyazaki, K Yamamoto, M Dohi - The journal of …, 2011 - journals.aai.org
Allergic inflammation in the airway is generally considered a Th2-type immune response.
However, Th17-type immune responses also play important roles in this process, especially in …

Clinical and radiological features of acute-onset diffuse interstitial lung diseases in patients with rheumatoid arthritis receiving treatment with biological agents …

…, Y Hasegawa, K Hatta, H Yamanaka, M Dohi… - Internal …, 2011 - jstage.jst.go.jp
Objective Acute-onset diffuse interstitial lung disease (AoDILD) in patients with rheumatoid
arthritis (RA) has been a serious concern, especially for those under treatment with biological …