The number of patients with atopic dermatitis is on the rise worldwide, and Japan is no
exception. According to recent estimates of the percentage of patients with atopic dermatitis in …

Mice subcutaneously injected with bleomycin, in an experimental model of human systemic
sclerosis, develop cutaneous and lung fibrosis with autoantibody production. CD19 is a …

Mice sc injected with bleomycin, an experimental model for human systemic sclerosis, develop
skin and lung fibrosis, which is mediated by inflammatory cell infiltration. This process is …

Objective To determine the prevalence, immunoglobulin subclass distribution, and clinical
correlation of antibodies (Abs), especially of IgE Abs, to BP180 and BP230 in patients with …

Objective Rapamycin, a novel macrolide immunosuppressive drug, is increasingly used as
an agent for posttransplant immunosuppression and treatment of autoimmune disease. The …

Introduction The high mobility group box 1 protein (HMGB-1)/advanced glycation end
products (RAGE) system is recently shown to play an important part in immune/inflammatory …

Immune cells are critical to the wound-healing process, through both cytokine and growth
factor secretion. Although previous studies have revealed that B cells are present within …

The formation of pressure ulcers is dependent on multiple factors including ischemia–reperfusion
(IR). This study assessed the mechanism of a previously reported murine model of …

Adult T‐cell leukemia/lymphoma (ATL) is a mature T‐cell neoplasm and is classified into
four subtypes (acute, lymphoma, chronic, and smoldering) according to the Shimoyama …

Platelets have been shown to be important in inflammation, but their role in the cutaneous
Arthus reaction remains unclear. To assess the role of platelets in this pathogenetic process, …