Objective The aim of this study was to evaluate the clinical characteristics of patients with
anti-melanoma differentiation–associated gene 5 (MDA5) antibody–positive inflammatory …

The clinical significance of anticyclic citrullinated peptide (CCP) antibodies in patients with
mixed connective tissue disease (MCTD) was assessed. Altogether, 86 sera from MCTD …

Background and objective Remodelling of pulmonary arteries (PA) contributes to the progression
of pulmonary hypertension (PH). Periostin, a matricellular protein, has been reported to …

In complement activation system, although the classical pathway has shown to play a critical
role for the pathogenesis of SLE, the role of lectin pathway has remained unknown in the …

Objective. To determine the degree of contribution and the contributing factors of ultrasound
in the diagnosis of rheumatoid arthritis (RA) in daily clinical practice and the predictive …

Objectives To determine the seroprevalence of anti-SARS-CoV-2 IgG and IgM antibodies in
symptomatic Japanese COVID-19 patients. Methods Serum samples (n = 114) from 34 …

Using 2-dimensional electrophoresis and ion-pair chromatography, we have identified
elements of proliferating cell nuclear antigen (PCNA) multiprotein complexes that are reactive to …

CD146, a transmembrane glycoprotein member of the immunoglobulin superfamily, acts as
an adhesion molecule that helps maintain the cell monolayer. Human endothelial cells …

Objectives. Treatment for rheumatoid arthritis (RA) should aim to achieve full remission. The
aim of this study was to investigate predictors of persistent subclinical synovitis and whether …

… IWAO SEKIGAWA'~', MASAKAZU MATSUSHITA~, SHOUSEKI LEE^, NOBUKI MAEDA'.
HITOSHI OGASAWARA', HIROSHI KANEKO', NOBORU IIDAa and HIROSHI HASHIMOTO' …