Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project
…, M Bortlík, BJA Crusius, M Vecchi, M Artieda… - Gut, 2013 - gut.bmj.com
Objective Through genome-wide association scans and meta-analyses thereof, over 70
genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs)) are significantly …
genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs)) are significantly …
Can we identify a power-oriented polygenic profile?
…, D Arteta, A Buxens, M Artieda… - Journal of Applied …, 2010 - journals.physiology.org
Using the model originally developed by Williams and Folland (J Physiol 586: 113–121,
2008), we determined 1) a “total genotype score” (TGS, from the accumulated combination of …
2008), we determined 1) a “total genotype score” (TGS, from the accumulated combination of …
Serum chitotriosidase activity is increased in subjects with atherosclerosis disease
M Artieda, A Cenarro, A Gañán, I Jericó… - … , and vascular biology, 2003 - Am Heart Assoc
Objective— This study was undertaken to analyze the relation between serum activity of
chitotriosidase enzyme, a protein synthesized exclusively by activated macrophages, and …
chitotriosidase enzyme, a protein synthesized exclusively by activated macrophages, and …
Reliable low-density DNA array based on allele-specific probes for detection of 118 mutations causing familial hypercholesterolemia
…, E Jiménez, M Lopez, MT Tejedor, M Artieda… - Clinical …, 2005 - academic.oup.com
Background: Patients with familial hypercholesterolemia (FH) have a high risk of premature
cardiovascular disease (PCVD). Mutations in the LDL receptor (LDLR) gene and the …
cardiovascular disease (PCVD). Mutations in the LDL receptor (LDLR) gene and the …
The −786 T/C polymorphism of the NOS3 gene is associated with elite performance in power sports
F Gómez-Gallego, JR Ruiz, A Buxens, M Artieda… - European Journal of …, 2009 - Springer
The NOS3 gene is a candidate to explain individual variations in health and exercise
related phenotypes. We compared genotypic and allelic frequencies of the NOS3 −786 T/C …
related phenotypes. We compared genotypic and allelic frequencies of the NOS3 −786 T/C …
Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
I Cleynen, E Vazeille, M Artieda, HW Verspaget… - Gut, 2014 - gut.bmj.com
Objective Altered microbiota composition, changes in immune responses and impaired
intestinal barrier functions are observed in IBD. Most of these features are controlled by …
intestinal barrier functions are observed in IBD. Most of these features are controlled by …
The− 174 G/C polymorphism of the IL6 gene is associated with elite power performance
The −174 G/C polymorphism [rs1800795] of the IL6 gene is a candidate to explain individual
variations in health and exercise related phenotypes. We compared −174 G/C genotypic …
variations in health and exercise related phenotypes. We compared −174 G/C genotypic …
[HTML][HTML] Tendon xanthomas in familial hypercholesterolemia are associated with a differential inflammatory response of macrophages to oxidized LDL
M Artieda, A Cenarro, C Junquera, P Lasierra… - FEBS letters, 2005 - Elsevier
Tendon xanthomas (TX) are pathognomonic lipid deposits commonly found in familial
hypercholesterolemia (FH) patients. The aim of this study was to determine whether macrophages …
hypercholesterolemia (FH) patients. The aim of this study was to determine whether macrophages …
Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance
C Santiago, JR Ruiz, A Buxens, M Artieda… - British Journal of …, 2011 - bjsm.bmj.com
In this study, allele and genotype frequencies of the ADRB1 Arg389Gly (rs1801253),
ADRB2 Gly16Arg (rs1042713) and Gln27Glu (rs1042714), and ADRB3 Trp64Arg (rs4994) …
ADRB2 Gly16Arg (rs1042713) and Gln27Glu (rs1042714), and ADRB3 Trp64Arg (rs4994) …
Can we predict top‐level sports performance in power vs endurance events? A genetic approach
A Buxens, JR Ruiz, D Arteta, M Artieda… - … journal of medicine …, 2011 - Wiley Online Library
The goal of our study was to discriminate potential genetic differences between humans who
are in both endpoints of the sports performance continuum (ie world‐class endurance vs …
are in both endpoints of the sports performance continuum (ie world‐class endurance vs …