The association between burnout and physical illness in the general population—results from the Finnish Health 2000 Study

T Honkonen, K Ahola, M Pertovaara, E Isometsä… - Journal of …, 2006 - Elsevier
OBJECTIVE: The association between burnout and physical diseases has been studied
very little. The purpose of this study was to examine the relationship between burnout and …

Clinical follow up study of 87 patients with sicca symptoms (dryness of eyes or mouth, or both)

M Pertovaara, M Korpela, H Uusitalo… - Annals of the …, 1999 - ard.bmj.com
OBJECTIVE To assess the prognosis of patients with sicca symptoms and to identify the clinical
and immunological factors that most sensitively predict the later development of primary …

High activity of indoleamine 2, 3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients

…, J Aittoniemi, SS Oja, A Raitala, J Laine, M Pertovaara… - Shock, 2010 - journals.lww.com
Indoleamine 2, 3-dioxygenase (IDO), which is the rate-limiting enzyme for tryptophan (trp)
catabolism, may play a critical role in various inflammatory disorders. Recent studies on …

Genetic association between interleukin‐10 promoter region polymorphisms and primary Sjögren's syndrome

J Hulkkonen, M Pertovaara, J Antonen… - … : Official Journal of …, 2001 - Wiley Online Library
Objective. To determine whether the haplotypes formed on the basis of single-base–exchange
polymorphisms at positions 1082, 819, or 592 of the interleukin-10 (IL-10) gene …

Effectiveness and drug survival of TNF inhibitors in the treatment of ankylosing spondylitis: a prospective cohort study

…, JT Joensuu, JP Lähteenmäki, MI Pertovaara… - The Journal of …, 2015 - jrheum.org
Objective. The aim of this research was to describe the effectiveness and drug survival of
tumor necrosis factor (TNF) inhibitors in the treatment of ankylosing spondylitis (AS) and to …

Novel carbonic anhydrase autoantibodies and renal manifestations in patients with primary Sjögren's syndrome

M Pertovaara, F Bootorabi, M Kuuslahti… - …, 2011 - academic.oup.com
Objective. Anti-carbonic anhydrase II (anti-CA II) antibodies have been related to renal
manifestations of primary SS (pSS), and animal studies have even suggested a pathogenic role …

Cytokine-induced STAT1 activation is increased in patients with primary Sjögren's syndrome

M Pertovaara, O Silvennoinen, P Isomäki - Clinical Immunology, 2016 - Elsevier
Limited data are available regarding the intracellular responses to different cytokines in
primary Sjögren's syndrome (pSS). We studied the signal transducer and activator of …

Th2 cytokine genotypes are associated with a milder form of primary Sjögren's syndrome

M Pertovaara, J Antonen, M Hurme - Annals of the rheumatic diseases, 2006 - ard.bmj.com
Background: Immunohistological studies on salivary and lacrimal glands have yielded
conflicting results on the Th1/Th2 balance in primary Sjögren’s syndrome (pSS). Objective: To …

Serum β2 microglobulin correlates with the new ESSDAI in patients with Sjögren's syndrome

M Pertovaara, M Korpela - Annals of the rheumatic diseases, 2011 - ard.bmj.com
1. Seror R, Ravaud P, Bowman SJ, et al. EULAR Sjogren’s syndrome disease activity index:
development of a consensus systemic disease activity index for primary Sjogren’s syndrome…

Autoimmunity and atherosclerosis: the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women. The Cardiovascular Risk in …

M Pertovaara, M Kähönen, M Juonala, T Laitinen… - …, 2009 - academic.oup.com
Objective. There is ample evidence demonstrating that accelerated atherosclerosis prevails
in autoimmune rheumatic diseases, particularly in SLE, and that the risk is due not only to …