Objective To determine whether aggressive treatment initiated early in the course of rheumatoid
factor (RF)–positive or RF‐negative polyarticular juvenile idiopathic arthritis (JIA) can …

BACKGROUND Undifferentiated systemic autoinflammatory diseases (USAIDs) present
diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine …

Objective To assess the efficacy and safety of rilonacept, an interleukin‐1 inhibitor, in a
randomized, double‐blind, placebo‐controlled trial. Methods An initial 4‐week double‐blind …

The Oxford Specialist Handbook of Paediatric Nephrology helps the reader understand and
manage all conditions affecting the kidney in childhood. This concise yet comprehensive …

The Lupus Family Registry and Repository (LFRR) was established with the goal of
assembling and distributing materials and data from families with one or more living members …

Objective. To determine the elapsed time while receiving aggressive therapy to the first
observation of clinically inactive disease (CID), total duration of CID and potential predictors of …

Background Prior studies have demonstrated abnormalities in the composition of the
gastrointestinal microbiota in pediatric and adult patients with spondyloarthritis (SpA). In particular, …

Objective. We surveyed pediatric rheumatologists (PR) in North America to learn how they
treat pediatric localized scleroderma (LS), a disease associated with significant morbidity for …

Objective To determine the relationships among race, income, and disease outcomes in
children with juvenile dermatomyositis (JDM). Study design Data from 438 subjects with JDM …

Objective Autoantibodies recognizing 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR)
are associated with statin exposure, the HLA allele DRB1*11:01, and necrotizing …