Objective Through genome-wide association scans and meta-analyses thereof, over 70
genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs)) are significantly …

Objective Altered microbiota composition, changes in immune responses and impaired
intestinal barrier functions are observed in IBD. Most of these features are controlled by …

Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in dogs
worldwide. Unfortunately, the success of eradication programs against this disease based …

Objectives. The aim of this study was to assess the involvement of the endoplasmic reticulum
aminopeptidase 1 (ERAP1) gene in AS susceptibility and functional severity in a Spanish …

Objective. The aim of this study was to develop a genetic prognostic tool to predict radiographic
progression towards severe disease in primary knee OA (KOA) patients. Methods. This …

Objective. The aim of this study was to analyse if single nucleotide polymorphisms (SNPs)
inside and outside the MHC region might improve the prediction of radiographic severity in AS…

The objective of this study is to identify single-nucleotide polymorphisms (SNPs) predictors
of treatment nonresponse to the first anti-TNF-alpha agent in ankylosing spondylitis (AS). …

… Jessica Polo y La Borda, PhD Magdalena Szczypiorska, PhD Nerea Bartolomé, PhD
José Campos, MD Brian J. Flores-Robles, MD Jesús Sanz, MD Cruz Fernández-Espartero …

Functional severity in ankylosing spondylitis (AS) patients is variable and difficult to predict
early. The aim of our study was to assess whether a combination of baseline clinical factors …

Objective. A recent genome-wide association study has identified 2 single-nucleotide
polymorphisms (SNP) associated with ankylosing spondylitis (AS), rs10865331 (2p15) and …