Diagnosing small fiber neuropathy in clinical practice: a deep phenotyping study

…, CM Altenschildesche, L Kreß… - Therapeutic …, 2021 - journals.sagepub.com
Background and aims: Small fiber neuropathy (SFN) is increasingly suspected in patients
with pain of uncertain origin, and making the diagnosis remains a challenge lacking a …

Differential impact of keratinocytes and fibroblasts on nociceptor degeneration and sensitization in small fiber neuropathy

L Kreß, L Hofmann, T Klein, K Klug, N Saffer, M Spitzel… - Pain, 2021 - journals.lww.com
Peripheral denervation and pain are hallmarks of small fiber neuropathy (SFN). We investigated
the contribution of skin cells on nociceptor degeneration and sensitization. We recruited …

Patient‐derived in vitro skin models for investigation of small fiber pathology

F Karl, M Wußmann, L Kreß… - Annals of Clinical …, 2019 - Wiley Online Library
Objective To establish individually expandable primary fibroblast and keratinocyte cultures
from 3‐mm skin punch biopsies for patient‐derived in vitro skin models to investigate of small …

Pain-associated mediators and axon pathfinders in fibromyalgia skin cells

D Evdokimov, L Kreß, P Dinkel, J Frank… - The Journal of …, 2020 - jrheum.org
Objective. To investigate whether the expression of cytokine, nociception-associated ion
channel, and axon guidance genes in patients with skin cell fibromyalgia syndrome (FMS) …

A translational study: Involvement of miR-21-5p in development and maintenance of neuropathic pain via immune-related targets CCL5 and YWHAE

F Karl-Schöller, M Kunz, L Kreß, M Held, N Egenolf… - Experimental …, 2022 - Elsevier
Neuropathic pain occurs in more than half of the patients suffering from peripheral neuropathies.
We investigated the role of microRNA (miR)-21 in neuropathic pain using a murine-…

[HTML][HTML] Distinguishing fibromyalgia syndrome from small fiber neuropathy: a clinical guide

…, N Egenolf, CM Zu Altenschildesche, L Kreß… - Pain …, 2024 - journals.lww.com
Objective: To comprehensively investigate clinical characteristics of women with FMS and
SFN to determine clinically applicable parameters for differentiation. Methods: We …

[HTML][HTML] Das Leitbild des Arbeitskreises Junge Schmerzgesellschaft–ein Blick in die Vergangenheit, Gegenwart und Zukunft

L Schouten, D Rosenberger, L Kreß, D Mauter… - Der Schmerz, 2023 - Springer
An dieser Stelle hatten wir 2022 bereits die Gelegenheit, unseren Arbeitskreis (AK), die „Junge
Schmerzgesellschaft “, unsere Projekte und unser Leitbild innerhalb der Deutschen …

Cross‐sectional study on patients' understanding and views of the informed consent procedure of a secondary stroke prevention trial

…, JM Reis, J Dores, V Pavlovic, L Kreß… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Improving understanding of study contents and procedures might
enhance recruitment into studies and retention during follow‐up. However, data in stroke …

[HTML][HTML] Cytokine expression profiles in white blood cells of patients with small fiber neuropathy

L Kreß, N Egenolf, C Sommer, N Üçeyler - BMC neuroscience, 2023 - Springer
Background The role of cytokines in the pathophysiology, diagnosis, and prognosis of small
fiber neuropathy (SFN) is incompletely understood. We studied expression profiles of …

Neuropathische Schmerzen

L Kreß, N Üçeyler - Neurologie up2date, 2020 - thieme-connect.com
Neuropathische Schmerzen begegnen ÄrztInnen aufgrund ihrer vielfältigen Ätiologie und
als mögliche Begleiterscheinung unterschiedlicher Krankheitsbilder in nahezu allen …