BACKGROUND. Long-term thyroid hormone (TH) therapy aiming at the suppression of
serum thyrotropin (TSH) has been traditionally used in the management of well differentiated …

Time perspective is a measure of the degree to which one's thinking is motivated by
considerations of the future, present, or past. Time perspective has been proposed as a potential …

Pathologically elevated serum levels of fibroblast growth factor-23 (FGF23), a bone-derived
hormone that regulates phosphorus homeostasis, result in renal phosphate wasting and …

Objective Thresholds of minimal clinically important improvement (MCII) are needed to plan
and interpret clinical trials. We estimated MCIIs for the rheumatoid arthritis (RA) activity …

McCune-Albright syndrome (MAS) is defined by the triad of café-au-lait skin pigmentation,
polyostotic fibrous dysplasia, and hyperfunctioning endocrinopathies, such as precocious …

Objective Despite wide use of the Short‐Form 36 (SF‐36) health survey in clinical trials of
rheumatoid arthritis (RA), estimates of minimum clinically important improvement (MCII) for its …

Familial tumoral calcinosis (FTC)/hyperostosis‐hyperphosphatemia syndrome (HHS) is a
rare disorder caused by mutations in the genes encoding fibroblast growth factor‐23 (FGF23), …

Fibrous dysplasia (FD) is a mosaic disease in which bone is replaced with fibro‐osseous
tissue. Lesions expand during childhood, reaching final burden by age 15 years. In vitro data …

Objective McCune–Albright syndrome (MAS) is a rare disorder with a broad spectrum
including precocious puberty (PP) due to recurrent estrogen-secreting ovarian cysts. This study …

Autosomal dominant hypocalcemia type 1 (ADH1) is a rare form of hypoparathyroidism
caused by heterozygous, gain‐of‐function mutations of the calcium‐sensing receptor gene (CAR)…