OBJECTIVE: The use of colchicine to prevent acute gout flares during initiation of allopurinol
therapy is widely practiced despite lack of proven benefit. We investigated if colchicine …

Irreversible electroporation (IRE) is a recent and minimally invasive method of partial prostate
ablation. However, knowledge of the essential landmarks of prostate anatomy is crucial to …

Various methods, including functional magnetic resonance imaging (fMRI), have recently
been developed to allow investigators to study functional activity in the living brain. Such …

Background: Rising rates of obesity have been reported in patients with inflammatory bowel
disease (IBD); however, prospective data is lacking. The aim of this study is to prospectively …

Personalized medicine is increasingly being employed across many areas of clinical practice,
as genes associated with specific diseases are discovered and targeted therapies are …

CO 2 storage in saline aquifers offers a realistic means of achieving globally significant
reductions in greenhouse gas emissions at the scale of billions of tonnes per year. We review …

… Using the 580V grating in the blue arm of the spectrograph gives a resolution R ∼ 1700,
while the 1000 R grating in the red arm results in R ∼ 4500. The wavelength range covered is …

Secure retention of CO 2 in geological reservoirs is essential for effective storage. Solubility
trapping, the dissolution of CO 2 into formation water, is a major sink on geological …

Objectives To assess the feasibility of local anaesthetic transperineal (LATP) technique
using a single‐freehand transperineal (TP) access device, and report initial prostate cancer (PCa…

Objectives Primary objectives: to determine whether local anaesthetic transperineal
prostate (LATP) biopsy improves the detection of clinically significant prostate cancer (csPCa), …