Gout provides some unique challenges in classification and measurement of outcomes. Our
aim was to evaluate criteria for classification and to develop and validate optimal …

• Four male subjects from two generations of a black family were found to have variable
expression of hypogammaglobulinemia (IgG, IgM, and IgA deficiency in two, IgA deficiency in …

Objective There is a lack of standardisation in the terminology used to describe gout. The
aim of this project was to develop a consensus statement describing the recommended …

Objective Existing criteria for the classification of gout have suboptimal sensitivity and/or
specificity, and were developed at a time when advanced imaging was not available. The …

Gout is a disorder that manifests as a spectrum of clinical and pathologic features built on a
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia, which …

The human immunodeficiency virus (HIV‐1) long terminal repeat (LTR) contains two binding
sites for NF‐kappa B in close proximity to three binding sites for the constitutive transcription …

In response to a request for proposal from the American College of Rheumatology (ACR), our
group was charged with developing nonpharmacologic and pharmacologic guidelines for …

• Occasionally patients with overlapping features of rheumatoid arthritis (RA) and systemic
lupus erythematosus (SLE), termed "rhupus," have been encountered. We wanted to …

Gout is a major health problem in the United States; it affects 8.3 million people, which is
approximately 4% of the adult population. Gout is most often diagnosed and managed in …

Uric acid has been long recognized as the cause of gouty arthritis and kidney stones. There
is mounting evidence that it may also have an important role in the development of vascular …