Non-radiative deactivation of the excited states of europium, terbium and ytterbium complexes by proximate energy-matched OH, NH and CH oscillators: an improved …
…, RS Dickins, S Faulkner, D Parker, L Royle… - Journal of the …, 1999 - pubs.rsc.org
The radiative rate constants for depopulation of the excited states of closely-related series of
anionic, neutral and cationic europium, terbium and ytterbium complexes have been …
anionic, neutral and cationic europium, terbium and ytterbium complexes have been …
HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software
L Royle, MP Campbell, CM Radcliffe, DM White… - Analytical …, 2008 - Elsevier
We present a robust, fully automatable technology platform that includes computer software
for the detailed analysis of low femtomoles of N-linked sugars released from glycoproteins. …
for the detailed analysis of low femtomoles of N-linked sugars released from glycoproteins. …
Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG
R Saldova, L Royle, CM Radcliffe, UM Abd Hamid… - …, 2007 - academic.oup.com
Ovarian cancer is the fourth most common cancer in women in the Western world. In a pilot
scale study, we highlight changes in the total serum glycome of patients with advanced …
scale study, we highlight changes in the total serum glycome of patients with advanced …
[HTML][HTML] Secretory IgA N-and O-glycans provide a link between the innate and adaptive immune systems
L Royle, A Roos, DJ Harvey, MR Wormald… - Journal of Biological …, 2003 - ASBMB
Secretory IgA (SIgA) is a multi-polypeptide complex consisting of a secretory component (SC)
covalently attached to dimeric IgA containing one joining (J) chain. We present the …
covalently attached to dimeric IgA containing one joining (J) chain. We present the …
GlycoBase and autoGU: tools for HPLC-based glycan analysis
MP Campbell, L Royle, CM Radcliffe, RA Dwek… - …, 2008 - academic.oup.com
The development of robust high-performance liquid chromatography (HPLC) technologies
continues to improve the detailed analysis and sequencing of glycan structures released from …
continues to improve the detailed analysis and sequencing of glycan structures released from …
Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins
R Peracaula, G Tabarés, L Royle, DJ Harvey… - …, 2003 - academic.oup.com
Prostate-specific antigen (PSA) is a glycoprotein secreted by prostate epithelial cells. PSA is
currently used as a marker of prostate carcinoma because high levels of PSA are indicative …
currently used as a marker of prostate carcinoma because high levels of PSA are indicative …
Proposal for a standard system for drawing structural diagrams of N‐ and O‐linked carbohydrates and related compounds
DJ Harvey, AH Merry, L Royle, M P. Campbell… - …, 2009 - Wiley Online Library
Symbolic diagrams are commonly used to depict N‐ and O‐linked glycans but there is no
general consensus as to how individual constituent monosaccharides or linkages are shown. …
general consensus as to how individual constituent monosaccharides or linkages are shown. …
Detailed Structural Analysis of N-Glycans Released From Glycoproteins in SDS-PAGE Gel Bands Using HPLC Combined With Exoglycosidase Array Digestions
L Royle, CM Radcliffe, RA Dwek, PM Rudd - Glycobiology protocols, 2007 - Springer
In contrast to the linear sequences of protein and DNA, oligosaccharides are branched
structures. In addition, almost all glycoproteins consist of a heterogeneous collection of differently …
structures. In addition, almost all glycoproteins consist of a heterogeneous collection of differently …
[PDF][PDF] Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein
…, GE Seabright, HB Kramer, DIR Spencer, L Royle… - Cell reports, 2016 - cell.com
The HIV-1 envelope glycoprotein trimer is covered by an array of N-linked glycans that shield
it from immune surveillance. The high density of glycans on the trimer surface imposes …
it from immune surveillance. The high density of glycans on the trimer surface imposes …
A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression
UM Abd Hamid, L Royle, R Saldova, CM Radcliffe… - …, 2008 - academic.oup.com
Aberrant glycosylation on glycoproteins that are either presented on the surface or secreted
by cancer cells is a potential source of disease biomarkers and provides insights into …
by cancer cells is a potential source of disease biomarkers and provides insights into …