Vitamin D deficiency in young children with severe acute lower respiratory infection

JD McNally, K Leis, LA Matheson… - Pediatric …, 2009 - Wiley Online Library
Rationale Acute lower respiratory infection (ALRI) is one of the most common reasons for
hospitalization and intensive care unit admission among children. Season related decreases in …

Characterization of the Flexcell™ Uniflex™ cyclic strain culture system with U937 macrophage-like cells

LA Matheson, NJ Fairbank, GN Maksym, JP Santerre… - Biomaterials, 2006 - Elsevier
Mechanical forces alter many cell functions in a variety of cell types. It has been recognized
that stimulation of cells in culture may be more representative of some physiologic conditions…

Vitamin D receptor (VDR) polymorphisms and severe RSV bronchiolitis: a systematic review and meta‐analysis

JD McNally, M Sampson, LA Matheson… - Pediatric …, 2014 - Wiley Online Library
Background A number of small studies have suggested a relationship between vitamin D
status and severe acute lower respiratory tract infection (ALRI), including RSV—bronchiolitis. …

Effect of polyurethane chemistry and protein coating on monocyte differentiation towards a wound healing phenotype macrophage

JE McBane, LA Matheson, S Sharifpoor, JP Santerre… - Biomaterials, 2009 - Elsevier
Tissue regeneration alternatives for peripheral vascular disease are actively being investigated;
however, few studies in this area have probed the role of the wound healing monocyte-…

Human macrophage-mediated biodegradation of polyurethanes: assessment of candidate enzyme activities

RS Labow, E Meek, LA Matheson, JP Santerre - Biomaterials, 2002 - Elsevier
A predominant cell type associated with explanted failed devices is the monocyte-derived
macrophage (MDM). However, there is still very little known about the specific cellular enzyme …

Biodegradation of polycarbonate‐based polyurethanes by the human monocyte‐derived macrophage and U937 cell systems

LA Matheson, RS Labow… - Journal of Biomedical …, 2002 - Wiley Online Library
The prominent cell type found on implanted medical devices during the chronic inflammatory
response is the monocyte‐derived macrophage (MDM). Using an activated in vitro cell …

Plant Sar1 isoforms with near-identical protein sequences exhibit different localisations and effects on secretion

SL Hanton, L Chatre, LA Matheson, M Rossi… - Plant molecular …, 2008 - Springer
In plants, differentiation of subdomains of the endoplasmic reticulum (ER) dedicated to
protein export, the ER export sites (ERES), is influenced by the type of export-competent …

Changes in macrophage function and morphology due to biomedical polyurethane surfaces undergoing biodegradation

LA Matheson, JP Santerre… - Journal of cellular …, 2004 - Wiley Online Library
Monocytes are recruited to the material surface of an implanted biomedical device recognizing
it as a foreign body. Differentiation into macrophages subsequently occurs followed by …

De novo formation of plant endoplasmic reticulum export sites is membrane cargo induced and signal mediated

SL Hanton, L Chatre, L Renna, LA Matheson… - Plant …, 2007 - academic.oup.com
The plant endoplasmic reticulum (ER) contains functionally distinct subdomains at which
cargo molecules are packed into transport carriers. To study these ER export sites (ERES), we …

Traffic between the plant endoplasmic reticulum and Golgi apparatus: to the Golgi and beyond

LA Matheson, SL Hanton, F Brandizzi - Current opinion in plant biology, 2006 - Elsevier
Significant advances have been made in recent years that have increased our understanding
of the trafficking to and from membranes that are functionally linked to the Golgi apparatus …