The aim of the study was to evaluate the frequency of extra-articular manifestations (EAMs)
of rheumatoid arthritis (RA) in a series of patients from nine Italian rheumatology clinics. A …

Background New drugs and new evidence concerning the use of established treatments have
become available since the publication of the first European League Against Rheumatism …

Objectives: To develop evidence based recommendations for the management of hand
osteoarthritis (OA). Methods: The multidisciplinary guideline development group comprised 16 …

… L Punzi12, … ≥2), hip OA (KL ≥2) and serum C-reactive protein (CRP) <5 mg/l. Of these,
gender, morning stiffness, family history, hip OA and CRP were not significant so were excluded …

Osteoarthritis, characterized by the breakdown of articular cartilage in synovial joints, has
long been viewed as the result of 'wear and tear' 1 . Although low-grade inflammation is …

Objectives: To develop evidence-based recommendations for the diagnosis of hand
osteoarthritis (OA). Methods: The multidisciplinary guideline development group, representing 15 …

Objectives To agree terminology and to develop recommendations for the diagnosis of calcium
pyrophosphate deposition (CPPD). Methods The European League Against Rheumatism …

… L Punzi19, … Morreale P, Manopulo R, Galati M, Boccanera L, Saponati G, Bocchi L. Comparison
of the antiinflammatory efficacy of chondroitin sulphate and diclofenac sodium in patients …

… 28 A small uncontrolled weight loss trial in 13 patients with gout showed that successful
weight loss reduced SUA from 570 μmol/l (95% CI, 520 to 620) at baseline to 470 μmol/l (420 to …

… L Punzi17, … Gabriel SE, Jaakkimainen L, Bombardier C. Risk for serious
gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs. A meta-analysis. …