INTRODUCTION Chromatin adopts an intricate three-dimensional (3D) organization in the
nucleus that is critical for many genome processes, from gene regulation to genome …

Age-related macular degeneration (AMD) was described for the first time in the 1840s and
is currently the leading cause of blindness for patients over 65 years in Western Countries. …

The establishment of cell types during development requires precise interactions between
genes and distal regulatory sequences. We have a limited understanding of how these …

Around 30–40% of patients with colorectal cancer (CRC) undergoing curative resection of
the primary tumour will develop metastases in the subsequent years 1 . Therapies to prevent …

Chronic kidney disease (CKD) is a highly prevalent disease that has become a public
health problem. Progression of CKD is associated with serious complications, including the …

… 2i–l). The LGR5 hi /KI67 lo cell population was specifically marked by MEX3A mRNA (Fig. …
l, Graphical summary of the key findings of the study. Data in c and f are presented as mean ± …

Purpose: To determine the efficacy of an in-office desensitizing paste containing 8% arginine
and calcium carbonate relative to that of a commercially-available pumice prophylaxis …

Objective: This paper presents the results of one of two eight-week dentin hypersensitivity
clinical studies in which the efficacy of a novel toothpaste containing 8.0% arginine, calcium …

Chromatin conformation capture (3C) methods and fluorescent in situ hybridization (FISH)
microscopy have been used to investigate the spatial organization of the genome. Although …

The use of classical smallpox vaccines based on vaccinia virus (VV) is associated with
severe complications in both naïve and immune individuals. Modified vaccinia virus Ankara (…