Hepatitis C virus (HCV), which is both a hepatotropic and a lymphotropic virus, has been
proposed as a possible causative agent of mixed cryoglobulinaemia. This ‘benign’ …

Objective: To investigate the possible role of HCV variants in the pathogenesis of mixed
cryoglobulinemia. Setting: Medical service (rheumatology and hepatology units) of urban, …

Oncogenesis is a multifactorial process in which environmental, genetic and infectious factors
are variably involved. A possible role of specific viruses has been suggested in at least 15…

Mixed cryoglobulinaemia (MC) is a systemic vasculitis, secondary to the deposition in small
and medium-sized blood vessels of circulating immune complexes, mainly the cryoglobulins, …

… lysis buffer containing 10 mmol/L EDTA, 1 mmol/L Tris-HC1 (pH 73… the addition of sodium
acetate 0.2 mol/L, transfert RNA, and 2 vol of … HCV PCR was performed using primers (Table l) …

Hepatitis C virus (HCV) infection is frequently found in autoimmune hepatitis and mixed
cryoglobulinaemia. In these conditions HCV could be responsible for immuno‐mediated organ …

… Sera were digested in four volumes of a lysis buffer containing 10 mmol/L EDTA, 1 mmol/L
Tris-HCL (pH 7.5), 1% sodium dodecyl sulphate, and 500 µg/mL proteinase K, extracted with …

… Tarantino A, Colesanti G: The role of circulat ing cryoglobulins and HBsAg in the pathogene
sis of glomerulonephritis of essential mixed cryoglobulinemia: in Chiandussi L. Bartoli E, …

with the possible contribution of both hemorheological and local factors. 1-5 Due to its clinical
and histological features, CV is classified among systemic vasculitides, in the subgroup of …

Peripheral neuropathy has been described in different rheumatic diseases such as rheumatoid
arthritis, systemic lupus erythematosus and systemic vasculitis, but usually in limited …