User profiles for Kunihiro Ichinose

Kunihiro Ichinose

Department of Immunology and Rheumatology, Division of Advanced Preventive Medical …
Verified email at nagasaki-u.ac.jp
Cited by 4944

Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome

…, T Kaneko, T Mizushima, K Ichinose… - Proceedings of the …, 2011 - National Acad Sciences
Nakajo-Nishimura syndrome (NNS) is a disorder that segregates in an autosomal recessive
fashion. Symptoms include periodic fever, skin rash, partial lipomuscular atrophy, and joint …

[HTML][HTML] M1 and M2 monocytes in rheumatoid arthritis: a contribution of imbalance of M1/M2 monocytes to osteoclastogenesis

…, T Koga, S Kawashiri, M Tamai, K Ichinose… - Frontiers in …, 2018 - frontiersin.org
Objectives We investigated the relationships among M1 monocytes, M2 monocytes, osteoclast
(OC) differentiation ability, and clinical characteristics in patients with rheumatoid arthritis (…

Recent advancement of understanding pathogenesis of type 1 diabetes and potential relevance to diabetic nephropathy

K Ichinose, E Kawasaki, K Eguchi - American journal of nephrology, 2007 - karger.com
Type 1 diabetes mellitus is an autoimmune disease characterized by progressive destruction
of pancreatic beta cells by genetic and environmental factors which leads to an absolute …

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model

K Ichinose, Y Maeshima, Y Yamamoto, H Kitayama… - Diabetes, 2005 - Am Diabetes Assoc
Diabetic nephropathy is one of the major microvascular complications in diabetes and is the
leading cause of end-stage renal disease worldwide. Among various factors, angiogenesis-…

A prediction rule for disease outcome in patients with undifferentiated arthritis using magnetic resonance imaging of the wrists and finger joints and serologic …

…, T Aramaki, SYA Kawashiri, K Ichinose… - Arthritis Care & …, 2009 - Wiley Online Library
Objective To evaluate whether magnetic resonance imaging (MRI) of the wrists and finger
joints and an analysis of serologic autoantibodies are clinically meaningful for the subsequent …

T cells and IL-17 in lupus nephritis

T Koga, K Ichinose, GC Tsokos - Clinical immunology, 2017 - Elsevier
Systemic lupus erythematosus (SLE) is a complicated autoimmune disorder characterized
by autoantibodies production, immune complex formation, and immune dysregulation, …

Toll-like receptor in salivary glands from patients with Sjögren's syndrome: functional analysis by human salivary gland cell line.

…, T Aramaki, K Arima, N Iwamoto, K Ichinose… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: We investigated expression of toll-like receptor (TLR) in labial salivary glands
of patients with Sjögren's syndrome (SS) and functional TLR expression in the cultured …

Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus

T Koga, K Ichinose, M Mizui, JC Crispín… - The Journal of …, 2012 - journals.aai.org
The activity of calcium/calmodulin-dependent protein kinase IV (CaMK4) is increased in T
cells from patients with systemic lupus erythematosus (SLE) and has been shown to reduce IL-…

Serum interferon-α is a useful biomarker in patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis

…, S Kawashiri, N Iwamoto, K Ichinose… - Modern …, 2015 - academic.oup.com
Objective. We have tried to clarify the clinical importance of the measurement of serum type-I
interferon (IFN) in patients with anti-melanoma differentiation-associated gene 5 Ab (MDA5 …

Ultrasonographic examination of rheumatoid arthritis patients who are free of physical synovitis: power Doppler subclinical synovitis is associated with bone erosion

…, Y Horai, A Okada, N Iwamoto, K Ichinose… - …, 2014 - academic.oup.com
Objective. The aim of this study was to investigate the characteristics of power Doppler (PD)
subclinical synovitis in patients with RA who achieve clinical remission free from physical …