Cardiovascular event risk in rheumatoid arthritis compared with type 2 diabetes: a 15-year longitudinal study

R Agca, LHGA Hopman, KJC Laan… - The Journal of …, 2020 - jrheum.org
Objective. Cardiovascular (CV) disease (CVD) risk is increased in rheumatoid arthritis (RA).
However, longterm followup studies investigating this risk are scarce. Methods. The CARRÉ (…

[HTML][HTML] Structural and mechanical comparison of human ear, alar, and septal cartilage

…, M Helder, N Kuzmin, K van der Laan… - … Surgery–Global Open, 2018 - journals.lww.com
Background: In the human ear and nose, cartilage plays a key role in establishing its form
and function. Interestingly, there is a noticeable paucity on biochemical, structural, and …

A fifteen-million-year surface- and subsurface-integrated TEX86 temperature record from the eastern equatorial Atlantic

CMH Van Der Weijst, KJ Van Der Laan… - Climate of the Past …, 2021 - cp.copernicus.org
TEX 86 is a paleothermometer based on Thaumarcheotal glycerol dialkyl glycerol tetraether
(GDGT) lipids and is one of the most frequently used proxies for sea-surface temperature (…

[HTML][HTML] Noninvasive measurement of ear cartilage elasticity on the cellular level: a new method to provide biomechanical information for tissue engineering

EJ Bos, K Van Der Laan, MN Helder… - … Surgery–Global Open, 2017 - journals.lww.com
Background: An important feature of auricular cartilage is its stiffness. To tissue engineer
new cartilage, we need objective tools to provide us with the essential biomechanical …

Evaluating flash freezing for preservation of rat abdominal aorta for delayed biomechanical characterization

KWF van der Laan, K Reesink, S Lambrichts… - bioRxiv, 2023 - biorxiv.org
Most studies investigating arterial stiffening use animal rather than human arteries. This is
because human tissue becomes available in small amounts and at irregular times, which …

[HTML][HTML] Improved Quantification of Cell Density in the Arterial Wall—A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy

KWF Van Der Laan, KD Reesink… - Frontiers in …, 2022 - frontiersin.org
Accurate information on vascular smooth muscle cell (VSMC) content, orientation, and
distribution in blood vessels is indispensable to increase understanding of arterial remodeling …

Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation

…, FW Asselbergs, SW van der Laan… - Nature cardiovascular …, 2022 - nature.com
Histopathological studies have revealed key processes of atherosclerotic plaque thrombosis.
However, the diversity and complexity of lesion types highlight the need for improved …

An inertial measurement unit based method to estimate hip and knee joint kinematics in team sport athletes on the field

…, EA Goedhart, D van der Laan… - JoVE (Journal of …, 2020 - jove.com
Current athlete monitoring practice in team sports is mainly based on positional data
measured by global positioning or local positioning systems. The disadvantage of these …

Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics

…, I Bot, B Slütter, SW Van Der Laan… - Circulation …, 2020 - Am Heart Assoc
… Slütter, and SW van der Laan participated in conceptualization, data interpretation, and
provided critical feedback on the article. SCA de Jager and E. Lutgens provided critical feedback …

[PDF][PDF] Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis

…, G Pasterkamp, SW van der Laan… - … heart journal open, 2022 - academic.oup.com
… 2 , Koen HM Prange … van der Laan … Nelson MR, Tipney H, Painter JL, Shen J, Nicoletti P,
Shen Y, Floratos A, Sham PC, Li MJ, Wang J, Cardon LR, Whittaker JC, Sanseau P. The support …