A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence

…, J Iber, E Nickerson, KL Wright… - Proceedings of the …, 1998 - National Acad Sciences
Sialic acids are important cell-surface molecules of animals in the deuterostome lineage.
Although humans do not express easily detectable amounts of N-glycolylneuraminic acid (…

[HTML][HTML] An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

J Chen, K Wright, JM Davis, P Jeraldo, EV Marietta… - Genome medicine, 2016 - Springer
Background The adaptive immune response in rheumatoid arthritis (RA) is influenced by an
interaction between host genetics and environment, particularly the host microbiome. …

Effect of therapy on radiographic progression in axial spondyloarthritis: a systematic review and meta‐analysis

…, E Myasoedova, CS Crowson, K Wright… - Arthritis & …, 2020 - Wiley Online Library
Objective To investigate the effect of therapies on radiographic progression in patients with
axial spondyloarthritis (SpA). Methods A comprehensive database search for studies …

Rheumatoid arthritis and pregnancy: safety considerations in pharmacological management

A Makol, K Wright, S Amin - Drugs, 2011 - Springer
Pregnancy can pose a challenge to the physician caring for women with rheumatoid arthritis
(RA). While many women with RA experience a spontaneous improvement in joint pain and …

The epidemiology of psoriatic arthritis over five decades: a Population‐Based study

…, MM Tollefson, K Wright - Arthritis & …, 2021 - Wiley Online Library
Objective To determine the incidence of psoriatic arthritis (PsA) in a US population and
describe trends in incidence and mortality over 5 decades. Methods The previously identified …

Cardiovascular comorbidity in rheumatic diseases: a focus on heart failure

K Wright, CS Crowson, SE Gabriel - Heart failure clinics, 2014 - heartfailure.theclinics.com
The increased risk of cardiovascular disease (CVD) associated with rheumatologic conditions
is well recognized and has been described extensively in systemic lupus erythematosus (…

Diagnostic delay in psoriatic arthritis: a population-based study

P Karmacharya, K Wright, SJ Achenbach… - The Journal of …, 2021 - jrheum.org
Objective To examine demographic and clinical characteristics associated with diagnostic
delay in psoriatic arthritis (PsA). Methods We characterized a retrospective, population-based …

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound‐Guided Synovial Biopsies in Rheumatoid Arthritis

…, R Ike, K Phillips, K Wright… - Arthritis & …, 2018 - Wiley Online Library
Objective Currently, there are no reliable biomarkers for predicting therapeutic response in
patients with rheumatoid arthritis ( RA ). The synovium may unlock critical information for …

Time trends in incidence, clinical features, and cardiovascular disease in ankylosing spondylitis over three decades: a population‐based study

KA Wright, CS Crowson, CJ Michet… - Arthritis care & …, 2015 - Wiley Online Library
Objective To determine trends in the incidence and clinical presentation of ankylosing
spondylitis (AS), the incidence of cardiovascular disease (CVD), and cardiovascular (CV) risk …

[HTML][HTML] Patient-provider discordance between global assessments of disease activity in rheumatoid arthritis: a comprehensive clinical evaluation

…, DE Schaffer, TLW Muskardin, K Wright… - Arthritis Research & …, 2017 - Springer
Background Discordance between patients with rheumatoid arthritis (RA) and their rheumatology
health care providers is a common and important problem. The objective of this study …