Objective Understanding of the personal risks for rheumatoid arthritis (RA) and other rheumatic
diseases remains poor, despite advances in knowledge with regard to their pathogenesis…

Background— CD4 T lymphocytes accumulate in unstable plaque. The direct and indirect
involvement of these T cells in tissue injury and plaque instability is not understood. Methods …

Background More than half of patients with polymyalgia rheumatica have a relapse during
tapering of glucocorticoid therapy. Previous studies have suggested that interleukin-6 …

OBJECTIVES: To evaluate the utility of erythrocyte sedimentation rate (ESR) and C-reactive
protein (CRP) for the diagnosis of giant cell arteritis (GCA) and to determine the frequency of …

Objective. The aim of this study was to compare baseline variables, treatment and outcomes
in patients with large-vessel GCA (LV-GCA), primarily of the upper extremities, with those …

Objectives To evaluate incidence-trends and timing of large-vessel (LV) manifestations in
patients with giant cell arteritis (GCA), and to examine the influence of LV manifestations on …

Objective To compare the efficacy of abatacept to that of placebo for the treatment of giant cell
arteritis (GCA). Methods In this multicenter trial, patients with newly diagnosed or relapsing …

Objectives To assess the accuracy of dual-energy CT (DECT) for diagnosing gout, and to
explore whether it can have any impact on clinical decision making beyond the established …

VEXAS syndrome (vacuoles in myeloid progenitors, E1 ubiquitin activating enzyme, X-linked,
autoinflammatory manifestations and somatic) is an autoinflammatory condition caused by …

Objectives To compare patterns of arteriographic lesions of the aorta and primary branches
in patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA). Methods Patients …