Association of autoantibodies against the phosphatidylserine–prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of …

…, M Ieko, ML Bertolaccini, K Ichikawa… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To clarify the association of autoantibodies against prothrombin with the clinical
manifestations of the antiphospholipid syndrome (APS) and with the presence of lupus …

Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1‐6 hepatocellular carcinoma model

…, Y Ozawa, K Kodama, J Ito, K Ichikawa… - Cancer …, 2018 - Wiley Online Library
Angiogenesis inhibitors such as lenvatinib and sorafenib, and an immune checkpoint
inhibitor ( ICI ), nivolumab, are used for anticancer therapies against advanced hepatocellular …

Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor.

…, Y Igarashi, M Fujimoto, K Ichikawa… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
Anticardiolipin antibodies (aCL) found in sera from patients with SLE react with cardiolipin (CL)
in the presence of a 50-kDa serum cofactor. The cofactor, which was identified to be beta …

Inhibition of FGFR reactivates IFNγ signaling in tumor cells to enhance the combined antitumor activity of lenvatinib with anti-PD-1 antibodies

Y Adachi, H Kamiyama, K Ichikawa, S Fukushima… - Cancer research, 2022 - AACR
FGFR pathway activation inhibits IFNγ signaling in tumor cells, and FGFR inhibition with
lenvatinib enhances antitumor immunity and the activity of anti-PD-1 antibodies. …

[HTML][HTML] Stress-induced translation of ATF5 mRNA is regulated by the 5′-untranslated region

Y Watatani, K Ichikawa, N Nakanishi, M Fujimoto… - Journal of Biological …, 2008 - ASBMB
Activating transcription factor (ATF) 5 is a transcription factor belonging to the ATF/cAMP-response
element-binding protein gene family. We previously reported that ATF5 mRNA …

Anticardiolipin antibody assay: a methodological analysis for a better consensus in routine determinations

…, G Balestrieri, T Koike, K Ichikawa… - Thrombosis and …, 2001 - thieme-connect.com
Despite the widely recognized practical importance of anticardiolipin (aCL) ELISA, the
reliability of this test has been recently discussed. In order to investigate this area on European …

Arterial disease and thrombosis in the antiphospholipid syndrome: a pathogenic role for endothelin 1

…, G Brooks, O Amengual, K Ichikawa… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To explore a possible correlation between endothelin 1 (ET‐1), the most potent
endothelium‐derived contracting factor that modulates vascular smooth muscle tone, and …

Antibodies to β2‐glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus

A Tsutsumi, E Matsuura, K Ichikawa… - … : Official Journal of …, 1996 - Wiley Online Library
Objective. To investigate whether anticardiolipin antibodies (aCL) in patients with systemic
lupus erythematosus (SLE) bind to β 2 ‐glycoprotein I (β 2 GPI), and to search for a …

High‐Temperature Properties of Unburned MgO‐C Bricks Containing Al and Si Powders

S Uchida, K Ichikawa, K Niihara - Journal of the American …, 1998 - Wiley Online Library
Changes in the mechanical and thermal properties, as well as in the microstructure, of unburned
MgO‐C bricks containing Al and Si powders were investigated at selected temperatures…

[PDF][PDF] MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP

K Ichikawa, Y Kubota, T Nakamura, JS Weng, T Tomida… - Molecular cell, 2015 - cell.com
The ERK pathway not only upregulates growth-promoting genes, but also downregulates
anti-proliferative and tumor-suppressive genes. In particular, ERK signaling contributes to …