Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
…, A Varela-Rohena, KM Haines… - Proceedings of the …, 2009 - National Acad Sciences
Mesothelin is a cell-surface molecule over-expressed on a large fraction of carcinomas, and
thus is an attractive target of immunotherapy. A molecularly targeted therapy for these …
thus is an attractive target of immunotherapy. A molecularly targeted therapy for these …
[PDF][PDF] Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma
Genetically modified T cells expressing chimeric antigen receptors (CARs) demonstrate
robust responses against lineage restricted, non-essential targets in hematologic cancers. …
robust responses against lineage restricted, non-essential targets in hematologic cancers. …
Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways.
…, LI Gold, BN Cronstein, KA Haines… - Proceedings of the …, 1991 - National Acad Sciences
Transforming growth factor beta 1 (TGF-beta 1), a homodimeric polypeptide (Mr 25,000),
derives from inflammatory cells and acts as a chemoattractant for monocytes and fibroblasts. …
derives from inflammatory cells and acts as a chemoattractant for monocytes and fibroblasts. …
Neutrophil gelatinase-associated lipocalin as a biomarker of disease activity in pediatric lupus nephritis
M Suzuki, KM Wiers, MS Klein-Gitelman, KA Haines… - Pediatric …, 2008 - Springer
We hypothesized that neutrophil gelatinase-associated lipocalin (NGAL) is an early predictive
biomarker of disease activity in lupus nephritis. NGAL in serial plasma (PNGAL) and urine …
biomarker of disease activity in lupus nephritis. NGAL in serial plasma (PNGAL) and urine …
Neutrophil gelatinase–associated lipocalin is a predictor of the course of global and renal childhood‐onset systemic lupus erythematosus disease activity
…, J Olson, NG Singer, KA Haines… - Arthritis & …, 2009 - Wiley Online Library
Objective To determine whether neutrophil gelatinase–associated lipocalin (NGAL) can
predict worsening of global and renal disease activity in childhood‐onset systemic lupus …
predict worsening of global and renal disease activity in childhood‐onset systemic lupus …
Effect of the interval between pregnancies on perinatal outcomes among white and black women
BP Zhu, KM Haines, T Le, K McGrath-Miller… - American journal of …, 2001 - Elsevier
Objective: We evaluated interpregnancy interval in relation to adverse perinatal outcomes
and whether the relationship differed by race. Study Design: We analyzed the vital statistics …
and whether the relationship differed by race. Study Design: We analyzed the vital statistics …
Consensus treatment plans for chronic nonbacterial osteomyelitis refractory to nonsteroidal antiinflammatory drugs and/or with active spinal lesions
…, SM Stern, JA Dvergsten, KA Haines… - Arthritis Care & …, 2018 - Wiley Online Library
Objective To develop standardized treatment regimens for chronic nonbacterial osteomyelitis
(CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), to enable …
(CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), to enable …
[HTML][HTML] BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia
Chimeric antigen receptor (CAR) T cells have induced remarkable antitumor responses in B
cell malignancies. Some patients do not respond because of T cell deficiencies that hamper …
cell malignancies. Some patients do not respond because of T cell deficiencies that hamper …
Law student idealism and job choice: some new data on an old question
HS Erlanger, CR Epp, M Cahill, KM Haines - Law & Society Review, 1996 - cambridge.org
Numerous commentaries and empirical studies have suggested that while a substantial
proportion of incoming law students are interested in careers in “public interest law,” by the time …
proportion of incoming law students are interested in careers in “public interest law,” by the time …
[PDF][PDF] Constitutive noncanonical NFκB signaling in pancreatic cancer cells
CE Wharry, KM Haines, RG Carroll… - Cancer biology & …, 2009 - Taylor & Francis
Constitutive classical NF-κB activation has been implicated in the development of pancreatic
cancer, and inhibition of classical NF-κB signaling sensitizes pancreatic cancer cells to …
cancer, and inhibition of classical NF-κB signaling sensitizes pancreatic cancer cells to …