Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
…, M Dherani, SA Madhi, RJ Singleton, KL O'Brien… - The Lancet, 2010 - thelancet.com
Background The global burden of disease attributable to respiratory syncytial virus (RSV)
remains unknown. We aimed to estimate the global incidence of and mortality from episodes of …
remains unknown. We aimed to estimate the global incidence of and mortality from episodes of …
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
KL O'brien, LJ Wolfson, JP Watt, E Henkle… - The Lancet, 2009 - thelancet.com
Background Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis,
and sepsis in children worldwide. However, many countries lack national estimates of …
and sepsis in children worldwide. However, many countries lack national estimates of …
[HTML][HTML] Global burden of childhood pneumonia and diarrhoea
Diarrhoea and pneumonia are the leading infectious causes of childhood morbidity and
mortality. We comprehensively reviewed the epidemiology of childhood diarrhoea and …
mortality. We comprehensively reviewed the epidemiology of childhood diarrhoea and …
[HTML][HTML] Safety and efficacy of a pentavalent human–bovine (WC3) reassortant rotavirus vaccine
…, A Karvonen, JP Watt, KL O'Brien… - … England Journal of …, 2006 - Mass Medical Soc
Background Rotavirus is a leading cause of childhood gastroenteritis and death worldwide.
Methods We studied healthy infants approximately 6 to 12 weeks old who were randomly …
Methods We studied healthy infants approximately 6 to 12 weeks old who were randomly …
[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a …
T Shi, DA McAllister, KL O'Brien, EAF Simoes… - The Lancet, 2017 - thelancet.com
Background We have previously estimated that respiratory syncytial virus (RSV) was associated
with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in …
with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in …
[HTML][HTML] Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression
Background Knowing whether COVID-19 vaccine effectiveness wanes is crucial for
informing vaccine policy, such as the need for and timing of booster doses. We aimed to …
informing vaccine policy, such as the need for and timing of booster doses. We aimed to …
[HTML][HTML] Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national …
B Wahl, KL O'Brien, A Greenbaum… - The Lancet Global …, 2018 - thelancet.com
Background Pneumococcal conjugate vaccine (PCV) and Haemophilus influenzae type b (Hib)
vaccine are now used in most countries. To monitor global and regional progress …
vaccine are now used in most countries. To monitor global and regional progress …
Functional deactivations: change with age and dementia of the Alzheimer type
…, AZ Snyder, M Bhakta, KC O'Brien… - Proceedings of the …, 2003 - National Acad Sciences
Young adults typically deactivate specific brain regions during active task performance.
Deactivated regions overlap with those that show reduced resting metabolic activity in aging and …
Deactivated regions overlap with those that show reduced resting metabolic activity in aging and …
[PDF][PDF] Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies
BACKGROUND: Although radiological pneumonia is used as an outcome measure in
epidemiological studies, there is considerable variability in the interpretation of chest radiographs. …
epidemiological studies, there is considerable variability in the interpretation of chest radiographs. …
[HTML][HTML] Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative …
Background The recent series of reviews conducted within the Global Action Plan for
Pneumonia and Diarrhoea (GAPPD) addressed epidemiology of the two deadly diseases at the …
Pneumonia and Diarrhoea (GAPPD) addressed epidemiology of the two deadly diseases at the …