[HTML][HTML] Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and …

…, DF Marker, CN Schreiner, DA Strickland, KM Wilton… - Virology, 2012 - Elsevier
The NF-kB family of transcription factors regulates important biological functions including cell
growth, survival and the immune response. We found that Human Papillomavirus type 16 (…

[HTML][HTML] Malignancy incidence, management, and prevention in patients with rheumatoid arthritis

KM Wilton, EL Matteson - Rheumatology and therapy, 2017 - Springer
Traditional and biologic disease-modifying antirheumatic drugs (DMARDs) are effective
medications for the management of rheumatoid arthritis (RA). However, the effects of these …

[HTML][HTML] Inhibition of the epidermal growth factor receptor by erlotinib prevents immortalization of human cervical cells by Human Papillomavirus type 16

…, MA Moses, SA Searleman, DA Stevens, KM Wilton… - Virology, 2011 - Elsevier
The Human Papillomavirus type-16 (HPV-16) E6 and E7 oncogenes are selectively
retained and expressed in cervical carcinomas, and expression of E6 and E7 is sufficient to …

Profound intellectual disability caused by homozygous TRAPPC9 pathogenic variant in a man from Malta

KM Wilton, LB Gunderson, L Hasadsri… - … Genetics & Genomic …, 2020 - Wiley Online Library
Background Intellectual disability is a complex multi‐faceted condition with diverse underlying
etiologies. One rare form of intellectual disability is secondary to the loss of TRAPPC9, an …

Malignancy incidence in patients with psoriatic arthritis: a comparison cohort-based incidence study

KM Wilton, CS Crowson, EL Matteson - Clinical rheumatology, 2016 - Springer
Malignancy is a major cause of death in patients with inflammatory disease. The risk of
individual malignancies is altered in some inflammatory diseases, such as rheumatoid arthritis …

Posttransplant autoimmune encephalitis

…, WJ Hogan, JJ Poterucha, KM Wilton… - Neurology …, 2018 - AAN Enterprises
The causes of encephalopathy in the posttransplant setting are diverse and include
medication toxicity (eg, posterior reversible encephalopathy syndrome), infections (eg, human …

NKG2D–DAP10 signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity

KM Wilton, BL Overlee… - Journal of cell …, 2020 - journals.biologists.com
Natural killer (NK) cells eliminate abnormal cells through the release of cytolytic granule
contents. In this process, NK cells must adhere to target cells through integrin-mediated …

Developmental brain abnormalities and acute encephalopathy in a patient with myopathy with extrapyramidal signs secondary to pathogenic variants in MICU1

KM Wilton, JA Morales‐Rosado, D Selcen… - JIMD …, 2020 - Wiley Online Library
Mitochondria play a variety of roles in the cell, far beyond their widely recognized role in
ATP generation. One such role is the regulation and sequestration of calcium, which is done …

[HTML][HTML] NK cell defects in X-linked pigmentary reticulate disorder

P Starokadomskyy, KM Wilton, K Krzewski, A Lopez… - JCI insight, 2019 - ncbi.nlm.nih.gov
X-linked reticulate pigmentary disorder (XLPDR, Mendelian Inheritance in Man# 301220) is
a rare syndrome characterized by recurrent infections and sterile multiorgan inflammation. …

Novel assessment of interstitial lung disease using the “Computer-Aided Lung Informatics for Pathology Evaluation and Rating”(CALIPER) software system in …

P Ungprasert, KM Wilton, FC Ernste, S Kalra… - Lung, 2017 - Springer
Purpose To evaluate the correlation between measurements from quantitative thoracic high-resolution
CT (HRCT) analysis with “Computer-Aided Lung Informatics for Pathology …