Mice subcutaneously injected with bleomycin, in an experimental model of human systemic
sclerosis, develop cutaneous and lung fibrosis with autoantibody production. CD19 is a …

Purpose: To study changes in the lid margin and meibomian glands and their association
with aging, sex, and tear function. Methods: We examined 354 eyes in 177 subjects (76 men …

Object. Thrombomodulin is a thrombin receptor on vascular endothelial cells that is highly
expressed when these cells are injured, and it has anticoagulating activity. The authors …

Mice sc injected with bleomycin, an experimental model for human systemic sclerosis, develop
skin and lung fibrosis, which is mediated by inflammatory cell infiltration. This process is …

Objective Rapamycin, a novel macrolide immunosuppressive drug, is increasingly used as
an agent for posttransplant immunosuppression and treatment of autoimmune disease. The …

Magnetoliposomes (MLs) conjugated with an antibody fragment to give specificity to a tumor
were applied to hyperthermia for cancer. The Fab' fragment of the G250 antibody, which …

Intensive physical exercise may cause muscular injury and increase oxidative stress. The
purpose of this study was to examine the effect of an antioxidant, coenzyme Q10 (CoQ10), on …

CD28 molecule expression on the surface of T cells plays a critical role in upregulation of
various cytokines synthesis and T-helper (Th) cell proliferation and differentiation. However, …

Introduction The high mobility group box 1 protein (HMGB-1)/advanced glycation end
products (RAGE) system is recently shown to play an important part in immune/inflammatory …

Immune cells are critical to the wound-healing process, through both cytokine and growth
factor secretion. Although previous studies have revealed that B cells are present within …