Brain morphology associated with obstructive sleep apnea
PM Macey, LA Henderson, KE Macey… - American journal of …, 2002 - atsjournals.org
Obstructive sleep apnea (OSA) is characterized by repeated occurrences of hypoxic,
hypercapnic, and transient blood pressure elevation episodes that may damage or alter neural …
hypercapnic, and transient blood pressure elevation episodes that may damage or alter neural …
A method for removal of global effects from fMRI time series
We present a technique for removing global effects from functional magnetic resonance
imaging (fMRI) images, using a voxel-level linear model of the global signal (LMGS). The …
imaging (fMRI) images, using a voxel-level linear model of the global signal (LMGS). The …
[HTML][HTML] A controlled trial of valganciclovir as induction therapy for cytomegalovirus retinitis
…, S Walmsley, RA Wolitz, K Macey… - … England Journal of …, 2002 - Mass Medical Soc
Background Valganciclovir is an orally administered prodrug that is rapidly hydrolyzed to
ganciclovir. We compared the effects of oral valganciclovir with those of intravenous ganciclovir …
ganciclovir. We compared the effects of oral valganciclovir with those of intravenous ganciclovir …
Longterm safety of patients receiving rituximab in rheumatoid arthritis clinical trials
…, R Fleischmann, DE Furst, K Macey… - The Journal of …, 2010 - jrheum.org
Objective. To evaluate the longterm safety of rituximab in clinical trials in patients with
rheumatoid arthritis (RA). Methods. Pooled analysis of safety data, including adverse events (AE) …
rheumatoid arthritis (RA). Methods. Pooled analysis of safety data, including adverse events (AE) …
Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients
…, C Gilbert, N Roberts, K Macey… - The Journal of …, 2004 - academic.oup.com
We investigated the emergence of cytomegalovirus (CMV) ganciclovir-resistance mutations
in 301 high-risk solid-organ transplant (SOT) recipients after oral prophylaxis, for 100 days, …
in 301 high-risk solid-organ transplant (SOT) recipients after oral prophylaxis, for 100 days, …
fMRI responses to cold pressor challenges in control and obstructive sleep apnea subjects
Obstructive sleep apnea (OSA) patients exhibit altered sympathetic outflow, which may reveal
mechanisms underlying the syndrome. We used functional MRI (fMRI) in 16 control and 10 …
mechanisms underlying the syndrome. We used functional MRI (fMRI) in 16 control and 10 …
Brain responses associated with the Valsalva maneuver revealed by functional magnetic resonance imaging
LA Henderson, PM Macey, KE Macey… - Journal of …, 2002 - journals.physiology.org
The Valsalva maneuver, a test frequently used to evaluate autonomic function, recruits
discrete neural sites. The time courses of neural recruitment relative to accompanying …
discrete neural sites. The time courses of neural recruitment relative to accompanying …
Hypoxia reveals posterior thalamic, cerebellar, midbrain, and limbic deficits in congenital central hypoventilation syndrome
PM Macey, MA Woo, KE Macey… - Journal of Applied …, 2005 - journals.physiology.org
Congenital central hypoventilation syndrome (CCHS) patients show deficient respiratory
and cardiac responses to hypoxia and hypercapnia, despite apparently intact arousal …
and cardiac responses to hypoxia and hypercapnia, despite apparently intact arousal …
Hypercapnic exposure in congenital central hypoventilation syndrome reveals CNS respiratory control mechanisms
…, PM Macey, MA Woo, KE Macey… - Journal of …, 2005 - journals.physiology.org
Congenital central hypoventilation syndrome (CCHS) patients show impaired ventilatory
responses and loss of breathlessness to hypercapnia, yet arouse from sleep to high CO 2 , …
responses and loss of breathlessness to hypercapnia, yet arouse from sleep to high CO 2 , …
Neural responses during Valsalva maneuvers in obstructive sleep apnea syndrome
…, MA Woo, PM Macey, KE Macey… - Journal of Applied …, 2003 - journals.physiology.org
The repetitive upper airway muscle atonic episodes and cardiovascular sequelae of obstructive
sleep apnea (OSA) suggest dysfunction of specific neural sites that integrate afferent …
sleep apnea (OSA) suggest dysfunction of specific neural sites that integrate afferent …