Prednisone versus prednisone plus ciclosporin versus prednisone plus methotrexate in new-onset juvenile dermatomyositis: a randomised trial
…, B Magnusson, G Sterba, T Avcin, K Brochard… - The Lancet, 2016 - thelancet.com
Background Most data for treatment of dermatomyositis and juvenile dermatomyositis are
from anecdotal, non-randomised case series. We aimed to compare, in a randomised trial, the …
from anecdotal, non-randomised case series. We aimed to compare, in a randomised trial, the …
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing
…, R Olaso, JF Deleuze, J Baruteau, K Brochard… - Nature Genetics, 2020 - nature.com
Inappropriate stimulation or defective negative regulation of the type I interferon response
can lead to autoinflammation. In genetically uncharacterized cases of the type I …
can lead to autoinflammation. In genetically uncharacterized cases of the type I …
Population Pharmacokinetics and Pharmacogenetics of Tacrolimus in De Novo Pediatric Kidney Transplant Recipients
W Zhao, V Elie, G Roussey, K Brochard… - Clinical …, 2009 - Wiley Online Library
The aim of this study was to develop a population pharmacokinetic model of tacrolimus in
pediatric kidney transplant patients, identify factors that explain variability, and determine …
pediatric kidney transplant patients, identify factors that explain variability, and determine …
Phenotype–genotype correlation in antenatal and neonatal variants of Bartter syndrome
K Brochard, O Boyer, A Blanchard… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Ante/neonatal Bartter syndrome (BS) is a hereditary salt-losing tubulopathy
due to mutations in genes encoding proteins involved in NaCl reabsorption in the thick …
due to mutations in genes encoding proteins involved in NaCl reabsorption in the thick …
[PDF][PDF] Mutations of CEP83 cause infantile nephronophthisis and intellectual disability
…, A Frigo, O Alibeu, C Masson, K Brochard… - The American Journal of …, 2014 - cell.com
Ciliopathies are a group of hereditary disorders associated with defects in cilia structure and
function. The distal appendages (DAPs) of centrioles are involved in the docking and …
function. The distal appendages (DAPs) of centrioles are involved in the docking and …
Safety and efficacy of rituximab in severe juvenile dermatomyositis: results from 9 patients from the French Autoimmunity and Rituximab registry
…, A Faye, V Guigonis, A Pagnier, K Brochard… - The Journal of …, 2011 - jrheum.org
Objective. To evaluate the safety and efficacy of rituximab (RTX) in juvenile dermatomyositis
(JDM) in off-trial patients. Methods. We conducted a multicenter prospective study of …
(JDM) in off-trial patients. Methods. We conducted a multicenter prospective study of …
Phase II open label study of Anakinra in intravenous immunoglobulin–resistant Kawasaki disease
I Koné‐Paut, S Tellier, A Belot, K Brochard… - Arthritis & …, 2021 - Wiley Online Library
Objective Anakinra has been shown to be successful in preventing and treating cardiovascular
lesions both in experimental murine models of Kawasaki disease (KD) and in several …
lesions both in experimental murine models of Kawasaki disease (KD) and in several …
Efficacy and safety of eculizumab in pediatric patients affected by Shiga toxin–related hemolytic and uremic syndrome: a randomized, placebo-controlled trial
A Garnier, K Brochard, T Kwon… - Journal of the …, 2023 - journals.lww.com
Background Shiga toxin–related hemolytic uremic syndrome (STEC-HUS) in children is a
severe condition, resulting in approximately 50% of patients requiring RRT. Furthermore, at …
severe condition, resulting in approximately 50% of patients requiring RRT. Furthermore, at …
Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal‐transplant …
…, G Deschênes, G Roussey, K Brochard… - The Journal of …, 2010 - Wiley Online Library
The objective was to develop a population pharmacokinetic‐pharmacogenetic model of
mycophenolic acid following administration of mycophenolate mofetil (MMF) in de novo pediatric …
mycophenolic acid following administration of mycophenolate mofetil (MMF) in de novo pediatric …
[HTML][HTML] Hypertension in children and adolescents: a position statement from a panel of multidisciplinary experts coordinated by the French Society of Hypertension
B Bouhanick, P Sosner, K Brochard… - Frontiers in …, 2021 - frontiersin.org
Hypertension is much less common in children than in adults. The group of experts decided
to perform a review of the literature to draw up a position statement that could be used in …
to perform a review of the literature to draw up a position statement that could be used in …