SIR, Recent genetic studies have demonstrated association between markers at 6q23 and
autoimmune conditions, including RA [1, 2] and SLE [3, 4]. For RA, independent disease …

Objective. Recent studies have identified 6q23 as an important susceptibility locus for rheumatoid
arthritis (RA), with risk alleles at 3 single-nucleotide polymorphisms combining to give …

Background/Aims Cerebellar ataxia is an uncommon neurological complication of Primary
Sjogren’s Syndrome (PSS), with case reports being the highest level of evidence available. …

Background: The Combined Obstetric and Rheumatology Clinic was established in
Sheffield in 2002 to support women with rheumatological conditions before and during their …

Background: IgG4 related fibrosclerosis is rare multi-system disease, characterised by IgG4+
plasma cells and T-lymphocytic infiltration of affected organs. Patients present to various …

Discussion: PAH is described in up to 10-20% of patients with Scleroderma, up to 10% in
SLE but is rare in Sjö gren’s. In a cohort of 107 patients with Sjö gren’sa full prospective …

A 82-year-old lady with known lcSSc, pulmonary hypertension, primary biliary cirrhosis and
paroxysmal atrial fibrillation was admitted for elective total hip arthroplasty. Her regular …

Background: Baricitinib is an oral reversible inhibitor of janus kinase enzymes 1 and 2. It is
licensed for use in moderate to severe rheumatoid arthritis that has failed to respond to other …

Methods: She presented with fatigue, intermittent fevers, arthralgia, neutropenia, anaemia (normocytic)
with cervical lymphadenopathy and raised inflammatory markers (CRP 157, ESR …