Objective To develop and validate revised classification criteria for granulomatosis with
polyangiitis (GPA). Methods Patients with vasculitis or comparator diseases were recruited into …

Objective To develop and validate revised classification criteria for eosinophilic granulomatosis
with polyangiitis (EGPA). Methods Patients with vasculitis or comparator diseases were …

Objective To develop and validate classification criteria for microscopic polyangiitis (MPA).
Methods Patients with vasculitis or comparator diseases were recruited into an international …

Endothelial cell-cell junctional proteins and cortical actin are of central importance for
regulating vascular permeability. Rap1, a member of the Ras family of GTPases, is enriched at …

Objective To develop and validate new classification criteria for Takayasu arteritis (TAK).
Methods Patients with vasculitis or comparator diseases were recruited into an international …

Phagocytosis of complement-opsonized targets is a primary function of neutrophils at sites
of inflammation, and the clearance of neutrophils that have phagocytosed microbes is …

Introduction We investigated the clinical and serological features of patients with antineutrophil
cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in Japan using data from a …

Rhabdomyolysis is a serious syndrome caused by skeletal muscle injury and the subsequent
release of breakdown products from damaged muscle cells into systemic circulation 1 . …

Neutrophils are central players in the innate immune system. They generate neutrophil
extracellular traps (NETs), which protect against invading pathogens but are also associated with …

Histone deacetylase (HDAC) regulates gene expression by modifying chromatin structure.
Although changes in the expression and activities of HDAC may affect the course of kidney …