Objective To characterize the diversity and taxonomic relative abundance of the gut
microbiota in patients with never‐treated, recent‐onset psoriatic arthritis (PsA). Methods High‐…

The role of the gut microbiome in models of inflammatory and autoimmune disease is now
well characterized. Renewed interest in the human microbiome and its metabolites, as well as …

We engineered a machine learning approach, MSHub, to enable auto-deconvolution of gas
chromatography–mass spectrometry (GC–MS) data. We then designed workflows to enable …

Objective Although oral methotrexate (MTX) remains the anchor drug for rheumatoid arthritis
(RA), up to 50% of patients do not achieve a clinically adequate outcome. In addition, there …

Objective Reactive arthritis (ReA) is an inflammatory disorder occurring several weeks after
gastrointestinal or genitourinary tract infections. HLA –B27 positivity is considered a risk …

Perturbations of the intestinal microbiome have been observed in patients with new-onset
and chronic autoimmune inflammatory arthritis. However, it is currently unknown whether …

Background Perturbation of commensal intestinal microbiota has been associated with several
autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist (Il1rn −/− mice) …

From birth, humans coexist and coevolve with trillions of micro-organisms inhabiting most
body surfaces and cavities, referred to as the human microbiome. Advances in sequencing …

Objective To characterize the ecological effects of biologic therapies on the gut bacterial
and fungal microbiome in psoriatic arthritis (PsA)/spondyloarthritis (SpA) patients. Methods …

Objective Intestinal microbiota are associated with the development of inflammatory arthritis.
The aim of this study was to dissect intestinal mucosal immune responses in the preclinical …