[PDF][PDF] Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells

…, AG Tzioufas, B Malleret, J Brody, S Albani, J van Roon… - Immunity, 2019 - cell.com
Human mononuclear phagocytes comprise phenotypically and functionally overlapping
subsets of dendritic cells (DCs) and monocytes, but the extent of their heterogeneity and distinct …

[HTML][HTML] Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis

MC Zweers, TN de Boer, J van Roon… - Arthritis research & …, 2011 - Springer
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive loss of articular
cartilage, subchondral bone sclerosis, osteophyte formation, and synovial inflammation, …

Proinflammatory mediator–induced reversal of CD4+, CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

JMR Van Amelsfort, JAG van Roon… - Arthritis & …, 2007 - Wiley Online Library
van Amelsfort and van Roon contributed equally to this work. … van Amelsfort and van Roon
contributed equally to this work. … van Amelsfort and van Roon contributed equally to this work. …

The role of ectopic germinal centers in the immunopathology of primary Sjögren's syndrome: a systematic review

…, AA Kruize, JWJ Bijlsma, JAG van Roon - Seminars in arthritis and …, 2013 - Elsevier
OBJECTIVES: To determine whether the presence of germinal centers (GCs) in salivary
glands of patients with primary Sjögren's syndrome (pSS) is related to the severity of disease …

Neutrophil extracellular trap release is associated with antinuclear antibodies in systemic lupus erythematosus and anti-phospholipid syndrome

…, RDE Fritsch-Stork, JAG van Roon… - …, 2018 - academic.oup.com
Objectives Increased release of neutrophil extracellular traps (NETs) is implicated in the
activation of plasmacytoid dendritic cells, vascular disease and thrombosis in SLE and APS. …

The prognostic value of routinely performed minor salivary gland assessments in primary Sjögren's syndrome

…, FPJG Lafeber, JWJ Bijlsma, JAG van Roon - Annals of the …, 2014 - ard.bmj.com
Objectives To investigate the prognostic value of the lymphocytic focus score (LFS) and the
percentages of IgA+, IgM+ and IgG+ plasma cells for disease severity of primary Sjögren …

Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

…, JA van Roon, K Vos, DM van Westing… - Arthritis & …, 2010 - Wiley Online Library
Objective To analyze the relationship between the type I interferon (IFN) signature and clinical
response to rituximab in rheumatoid arthritis (RA) patients. Methods Twenty RA patients …

Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin‐10 and interleukin‐4

JAG van Roon, JLAM van Roy… - Arthritis & …, 1996 - Wiley Online Library
Objective. Inflammation‐induced articular cartilage degradation is a major problem in
rheumatoid arthritis (RA). Type 1 T cell activity (characterized by interferon‐γ/interleukin‐2 [IL‐2] …

Galectin-9 is an easy to measure biomarker for the interferon signature in systemic lupus erythematosus and antiphospholipid syndrome

LL van den Hoogen, JAG van Roon… - Annals of the …, 2018 - ard.bmj.com
Objective The interferon (IFN) signature is related to disease activity and vascular disease in
systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) and represents …

[PDF][PDF] Galectin‐9 and CXCL10 as biomarkers for disease activity in juvenile dermatomyositis: a longitudinal cohort study and multicohort validation

…, JAG van Roon, WL van der Pol… - Arthritis & …, 2019 - Wiley Online Library
Objective Objective evaluation of disease activity is challenging in patients with juvenile
dermatomyositis ( DM ) due to a lack of reliable biomarkers, but it is crucial to avoid both under‐ …