[PDF][PDF] Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells
Human mononuclear phagocytes comprise phenotypically and functionally overlapping
subsets of dendritic cells (DCs) and monocytes, but the extent of their heterogeneity and distinct …
subsets of dendritic cells (DCs) and monocytes, but the extent of their heterogeneity and distinct …
[HTML][HTML] Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis
MC Zweers, TN de Boer, J van Roon… - Arthritis research & …, 2011 - Springer
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive loss of articular
cartilage, subchondral bone sclerosis, osteophyte formation, and synovial inflammation, …
cartilage, subchondral bone sclerosis, osteophyte formation, and synovial inflammation, …
Proinflammatory mediator–induced reversal of CD4+, CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis
JMR Van Amelsfort, JAG van Roon… - Arthritis & …, 2007 - Wiley Online Library
… van Amelsfort and van Roon contributed equally to this work. … van Amelsfort and van Roon
contributed equally to this work. … van Amelsfort and van Roon contributed equally to this work. …
contributed equally to this work. … van Amelsfort and van Roon contributed equally to this work. …
The role of ectopic germinal centers in the immunopathology of primary Sjögren's syndrome: a systematic review
…, AA Kruize, JWJ Bijlsma, JAG van Roon - Seminars in arthritis and …, 2013 - Elsevier
OBJECTIVES: To determine whether the presence of germinal centers (GCs) in salivary
glands of patients with primary Sjögren's syndrome (pSS) is related to the severity of disease …
glands of patients with primary Sjögren's syndrome (pSS) is related to the severity of disease …
Neutrophil extracellular trap release is associated with antinuclear antibodies in systemic lupus erythematosus and anti-phospholipid syndrome
…, RDE Fritsch-Stork, JAG van Roon… - …, 2018 - academic.oup.com
Objectives Increased release of neutrophil extracellular traps (NETs) is implicated in the
activation of plasmacytoid dendritic cells, vascular disease and thrombosis in SLE and APS. …
activation of plasmacytoid dendritic cells, vascular disease and thrombosis in SLE and APS. …
The prognostic value of routinely performed minor salivary gland assessments in primary Sjögren's syndrome
…, FPJG Lafeber, JWJ Bijlsma, JAG van Roon - Annals of the …, 2014 - ard.bmj.com
Objectives To investigate the prognostic value of the lymphocytic focus score (LFS) and the
percentages of IgA+, IgM+ and IgG+ plasma cells for disease severity of primary Sjögren …
percentages of IgA+, IgM+ and IgG+ plasma cells for disease severity of primary Sjögren …
Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients
…, JA van Roon, K Vos, DM van Westing… - Arthritis & …, 2010 - Wiley Online Library
Objective To analyze the relationship between the type I interferon (IFN) signature and clinical
response to rituximab in rheumatoid arthritis (RA) patients. Methods Twenty RA patients …
response to rituximab in rheumatoid arthritis (RA) patients. Methods Twenty RA patients …
Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin‐10 and interleukin‐4
JAG van Roon, JLAM van Roy… - Arthritis & …, 1996 - Wiley Online Library
Objective. Inflammation‐induced articular cartilage degradation is a major problem in
rheumatoid arthritis (RA). Type 1 T cell activity (characterized by interferon‐γ/interleukin‐2 [IL‐2] …
rheumatoid arthritis (RA). Type 1 T cell activity (characterized by interferon‐γ/interleukin‐2 [IL‐2] …
Galectin-9 is an easy to measure biomarker for the interferon signature in systemic lupus erythematosus and antiphospholipid syndrome
LL van den Hoogen, JAG van Roon… - Annals of the …, 2018 - ard.bmj.com
Objective The interferon (IFN) signature is related to disease activity and vascular disease in
systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) and represents …
systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) and represents …
[PDF][PDF] Galectin‐9 and CXCL10 as biomarkers for disease activity in juvenile dermatomyositis: a longitudinal cohort study and multicohort validation
…, JAG van Roon, WL van der Pol… - Arthritis & …, 2019 - Wiley Online Library
Objective Objective evaluation of disease activity is challenging in patients with juvenile
dermatomyositis ( DM ) due to a lack of reliable biomarkers, but it is crucial to avoid both under‐ …
dermatomyositis ( DM ) due to a lack of reliable biomarkers, but it is crucial to avoid both under‐ …