Objective To evaluate the efficacy and safety of ustekinumab in 3 randomized, placebo‐controlled
studies in patients with axial spondyloarthritis (SpA). Studies 1 and 2 included patients …

Background Type 1 diabetes is an autoimmune disease characterized by progressive loss
of pancreatic beta cells. Golimumab is a human monoclonal antibody specific for tumor …

Objectives Assess golimumab's long-term efficacy/safety in psoriatic arthritis (PsA). Methods
Adults with active PsA (≥3 swollen and tender joints, active psoriasis) were randomly …

… Harrison,3 Lilianne Kim,3 Kim Hung Lo,3 Jocelyn H. … Harrison, Kim, Lo, Leu, and Hsia
own stock or stock options in Johnson & Johnson, of which Janssen Research & Development, …

Objective This report aims to determine the safety, pharmacokinetics (PK) and efficacy of
subcutaneous golimumab in active polyarticular-course juvenile idiopathic arthritis (polyJIA). …

Objective. To evaluate the safety and efficacy of intravenous golimumab (GOL) in patients
with active ankylosing spondylitis (AS). Methods. In a phase III, randomized, double-blind, …

Objective. To evaluate the safety and efficacy of golimumab (GOL), a human antitumor
necrosis factor antibody, in patients with active rheumatoid arthritis (RA) despite methotrexate (…

The metabolic profile of niacin is influenced by the rate of niacin administration. This study
characterizes the effect of administration rate on the pharmacokinetics of niacin and its …

Objective To evaluate the safety and efficacy of golimumab through 5 years in adults with
active rheumatoid arthritis (RA) who had not previously received methotrexate (MTX). Methods …

Therapeutic proteins may first be developed as intravenous (iv) therapies with new subcutaneous
(sc) dosage forms being subsequently developed to provide an alternative route of …