We report experiments and modeling of translocation of double-strand DNA through a
siliconoxide nanopore. Long DNA molecules with different lengths ranging from 6500 to 97000 …

Background The prevalence of chronic kidney disease is high in developing countries.
However, no national survey of chronic kidney disease has been done incorporating both …

Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems
1 . However, a comprehensive single-cell atlas has not been achieved for humans. Here …

Zygomorphic flowers, with bilateral (dorsoventral) symmetry, are considered to have evolved
several times independently in flowering plants. In Antirrhinum majus, floral dorsoventral …

Background and Objective: Hemodialysis (HD) patients are more inactive, leading to poor
functional capacity and quality of life; this may be reversed with intradialytic exercise training. …

For decades, lactic acid has been considered a dead-end product of glycolysis. Research in
the last 20+ years has shown otherwise. Through its transporters (MCTs) and receptor (…

Immunoglobin A (IgA) vasculitis (IgAV), formerly called the Henoch-Schönlein purpura (HSP),
is a small vessel vasculitis, characterized by IgA1-dominant immune deposition at …

Background Roxadustat (FG-4592) is an oral inhibitor of hypoxia-inducible factor (HIF)
prolyl hydroxylase that stimulates erythropoiesis and regulates iron metabolism. In phase 2 …

Artificially improving traits of cultivated alfalfa (Medicago sativa L.), one of the most important
forage crops, is challenging due to the lack of a reference genome and an efficient genome …

Background Acute kidney injury (AKI) has become a worldwide public health problem, but
little information is available about the disease burden in China. We aimed to evaluate the …