A pseudomembranous structure that has the histological characteristics of a foreign-body-like
reaction invariably develops at the bone-cement interface in the proximity of resorption of …

Serial studies have been performed on three patients with relapsing polychondritis in an
attempt to define a potential immunopathologic role for degradation constituents of cartilage in …

Tumor necrosis factor-a (TNF-a) inhibition, used in the treatment of rheumatoid arthritis (RA),
is associated with central nervous system (CNS) events including new onset and/or …

Few advances in our understanding of the polychondritic disease process have been made
within the past year. Clinical studies have emphasized pulmonary manifestations and newer …

Excerpt In recent years evidence has accumulated that immunological phenomena may be
involved, at least secondarily, in the pathogenesis of some of the rheumatic diseases. Similar …

Patients with rheumatoid arthritis have been studied in an attempt to detect immune responses
to cartilage antigens that might function in the causation and/or perpetuation of joint …

The secondary immune response to tetanus toxoid in 14 patients with rheumatoid arthritis (RA)
has been studied in suspension cultures of peripheral blood lymphocytes (PBL) and …

Nonenzymatic, trypsin sensitive cytokines derived from lectin stimulated normal human
mononuclear cells have been shown to induce release of proteoglycan and collagen degrading …

… Address reprint requests to Jerome H. Herman, MD, Division of Immunology, ML 563,
University of Cincinnati Medical Center, 231 Bethesda Avenue, Cincinnati, OH 45267. Submitted …

Nonsteroidal anti-inflammatory drugs have a potential for modifying the complex
pathophysiologic events leading to cartilage destruction in various forms of arthritis. Following an …