Incidence and long-term cost of steroid-related side effects after renal transplantation
Corticosteroids are an essential component of most immunosuppressive regimens currently
used in renal transplantation because of their efficacy in reducing acute rejection and …
used in renal transplantation because of their efficacy in reducing acute rejection and …
Risk of cardiovascular disease events in patients with type 2 diabetes prescribed the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide twice daily or other …
JH Best, BJ Hoogwerf, WH Herman, EM Pelletier… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE To test the hypothesis that exenatide twice daily reduces the relative incidence
of cardiovascular disease (CVD) events among patients with type 2 diabetes compared with …
of cardiovascular disease (CVD) events among patients with type 2 diabetes compared with …
[HTML][HTML] Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
JW Pierce, R Schoenleber, G Jesmok, J Best… - Journal of Biological …, 1997 - ASBMB
We have identified two compounds that inhibit the expression of endothelial-leukocyte adhesion
molecules intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-…
molecules intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-…
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
…, MD Conkright, G Canettieri, J Best… - Proceedings of the …, 2005 - National Acad Sciences
Hormones and nutrients often induce genetic programs via signaling pathways that interface
with gene-specific activators. Activation of the cAMP pathway, for example, stimulates …
with gene-specific activators. Activation of the cAMP pathway, for example, stimulates …
[HTML][HTML] The CREB coactivator TORC2 functions as a calcium-and cAMP-sensitive coincidence detector
RA Screaton, MD Conkright, Y Katoh, JL Best… - Cell, 2004 - cell.com
Elevations in circulating glucose and gut hormones during feeding promote pancreatic islet
cell viability in part via the calcium- and cAMP-dependent activation of the transcription factor …
cell viability in part via the calcium- and cAMP-dependent activation of the transcription factor …
[HTML][HTML] Clinical outcomes of patients with giant cell arteritis treated with tocilizumab in real-world clinical practice: decreased incidence of new visual manifestations
…, R Spiera, J Pei, PN Sidiropoulos, JH Best… - Arthritis Research & …, 2021 - Springer
Background Placebo-controlled clinical trials have demonstrated the efficacy of tocilizumab (TCZ)
for remission maintenance and glucocorticoid sparing in patients with giant cell …
for remission maintenance and glucocorticoid sparing in patients with giant cell …
[HTML][HTML] The association of the treatment with glucagon-like peptide-1 receptor agonist exenatide or insulin with cardiovascular outcomes in patients with type 2 …
Background To evaluate the association of treatment with glucagon-like peptide-1 (GLP-1)
receptor agonist exenatide and/or insulin on macrovascular outcomes in patients with type 2 …
receptor agonist exenatide and/or insulin on macrovascular outcomes in patients with type 2 …
Cost utility in the United States of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone for the treatment of elderly patients with diffuse large B …
JC Hornberger, JH Best - Cancer: Interdisciplinary International …, 2005 - Wiley Online Library
BACKGROUND Findings from the Groupe d'Etude des Lymphomes Adultes LNH 98‐5 study
showed that rituximab added to combined cyclophosphamide, doxorubicin, vincristine, and …
showed that rituximab added to combined cyclophosphamide, doxorubicin, vincristine, and …
Association between glucocorticoid exposure and healthcare expenditures for potential glucocorticoid-related adverse events in patients with rheumatoid arthritis
JH Best, AM Kong, GM Lenhart, K Sarsour… - The Journal of …, 2018 - jrheum.org
Objective. Oral glucocorticoid (OGC) use for rheumatoid arthritis (RA) is debated because of
the adverse event (AE) profile of OGC. We evaluated the associations between cumulative …
the adverse event (AE) profile of OGC. We evaluated the associations between cumulative …
Weight-related quality of life, health utility, psychological well-being, and satisfaction with exenatide once weekly compared with sitagliptin or pioglitazone after 26 …
JH Best, RR Rubin, M Peyrot, Y Li, P Yan… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE To assess change in patient-reported outcomes in subjects with type 2
diabetes treated with exenatide once weekly compared with those treated with sitagliptin or …
diabetes treated with exenatide once weekly compared with those treated with sitagliptin or …