[HTML][HTML] Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) …
…, J de Zoysa, LK Stamp, N Dalbeth, J Harré Hindmarsh… - Diabetologia, 2018 - Springer
Aims/hypothesis The A (minor) allele of CREBRF rs373863828 has been associated with
increased BMI and reduced risk of type 2 diabetes in the Samoan populations of Samoa and …
increased BMI and reduced risk of type 2 diabetes in the Samoan populations of Samoa and …
Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout
…, N Dalbeth, LK Stamp, JH Hindmarsh… - Annals of the …, 2020 - ard.bmj.com
Objective Gout is characterised by severe interleukin (IL)-1-mediated joint inflammation
induced by monosodium urate crystals. Since IL-37 is a pivotal anti-inflammatory cytokine …
induced by monosodium urate crystals. Since IL-37 is a pivotal anti-inflammatory cytokine …
Two-year results from a community-wide diabetes prevention intervention in a high risk indigenous community: the Ngati and Healthy project
…, SM Williams, S Abel, M Iles, JH Hindmarsh… - Diabetes research and …, 2009 - Elsevier
We describe changes in markers and prevalence of glucose metabolism disorders following
a 2-year community-wide intervention aimed at reducing insulin resistance (IR) prevalence …
a 2-year community-wide intervention aimed at reducing insulin resistance (IR) prevalence …
Population‐specific resequencing associates the ATP‐binding cassette subfamily C member 4 gene with gout in New Zealand Māori and Pacific men
…, RK Topless, JH Hindmarsh… - Arthritis & …, 2017 - Wiley Online Library
Objective There is no evidence for a genetic association between organic anion
transporters 1–3 (SLC22A6, SLC22A7, and SLC22A8) and multidrug resistance protein 4 (MRP4; …
transporters 1–3 (SLC22A6, SLC22A7, and SLC22A8) and multidrug resistance protein 4 (MRP4; …
[HTML][HTML] Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout
…, TL Jansen, A So, J Harré Hindmarsh… - Arthritis research & …, 2020 - Springer
Background The ABCG2 Q141K (rs2231142) and rs10011796 variants associate with
hyperuricaemia (HU). The effect size of ABCG2 rs2231142 on urate is ~ 60% that of SLC2A9, yet …
hyperuricaemia (HU). The effect size of ABCG2 rs2231142 on urate is ~ 60% that of SLC2A9, yet …
Mitochondrial genetic variation and gout in Māori and Pacific people living in Aotearoa New Zealand
…, J Boocock, N Dalbeth, JH Hindmarsh… - Annals of the …, 2018 - ard.bmj.com
Objective Mitochondria have an important role in the induction of the NLRP3 inflammasome
response central in gout. The objective was to test whether mitochondrial genetic variation …
response central in gout. The objective was to test whether mitochondrial genetic variation …
Effect of a health literacy intervention trial on knowledge about cardiovascular disease medications among Indigenous peoples in Australia, Canada and New Zealand
…, M Lambert, JK Smylie, S Reid, J Harré-Hindmarsh… - BMJ open, 2018 - bmjopen.bmj.com
Objectives To assess the effect of a customised, structured cardiovascular disease (CVD)
medication health literacy programme on medication knowledge among Indigenous people …
medication health literacy programme on medication knowledge among Indigenous people …
[HTML][HTML] Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares
…, PB Jones, LK Stamp, JH Hindmarsh… - BMC musculoskeletal …, 2015 - Springer
Background Gout is a consequence of an innate immune reaction to monosodium urate
crystals deposited in joints. Acute gout attacks can be triggered by dietary factors that are …
crystals deposited in joints. Acute gout attacks can be triggered by dietary factors that are …
[HTML][HTML] Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption
…, R Topless, JE Hollis-Moffatt, JH Hindmarsh… - Arthritis research & …, 2013 - Springer
Introduction The T allele of a single nucleotide polymorphism (SNP: rs2544390) in lipoprotein
receptor-related protein 2 (LRP2) is associated with higher serum urate and risk of gout in …
receptor-related protein 2 (LRP2) is associated with higher serum urate and risk of gout in …
Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus
…, ME Merriman, JH Hindmarsh… - The Journal of …, 2021 - jrheum.org
Objective The Māori and Pacific (Polynesian) population of Aotearoa New Zealand has a
high prevalence of gout. Our aim was to identify potentially functional missense genetic …
high prevalence of gout. Our aim was to identify potentially functional missense genetic …