Increased sialylation, especially involving the Sialyl-Lewis a and Sialyl-Lewis X determinants,
has been reported in breast cancer. A multiplex reverse transcription-PCR method was …

BRCA1-associated breast cancers (BRCA1-BCs) frequently harbor a high histoprognostic
grade, p53 alterations, and estrogen receptor negativity. Although these parameters predict a …

Background: Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play
essential roles in tumor invasion and metastasis. High levels of both uPA and PAI-1 are …

Importance Limited information about the relationship between specific mutations
inBRCA1orBRCA2(BRCA1/2) and cancer risk exists. Objective To identify mutation-specific cancer …

We show here that the neurotrophin nerve growth factor (NGF), which has been shown to
be a mitogen for breast cancer cells, also stimulates cell survival through a distinct signaling …

Strong inter- and intrafamilial variation of penetrance of breast and ovarian cancer is
observed in BRCA1 mutation carriers. The wild-type copy of the BRCA1 gene is a plausible …

We measured the expression of the type I growth factor receptor gene family [epidermal
growth factor receptor (EGFR), c-erbB-2, c-erbB-3 and c-erbB-4] in a series of 365 unselected …

The class of molecular chaperones known as 14-3-3 is involved in the control of cellular
growth by virtue of its apparent regulation of various signaling pathways, including the Raf/…

The Epstein-Barr virus (EBV) has been detected in subsets of breast cancers. In order to
elaborate on these observations, we quantified by real-time PCR (Q-PCR) the EBV genome in …

Objective Endostatin is an angiogenesis inhibitor derived from type XVIII collagen. The aim
of this study was to determine the concentrations of circulating endostatin in patients with …