Objective Early diffuse scleroderma (systemic sclerosis; SSc) has no proven treatment. This
study was undertaken to examine the efficacy of methotrexate (MTX) in improving the skin …

In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with
the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human …

Objective. Anticitrullinated protein antibodies (ACPA) are relatively specific for rheumatoid
arthritis (RA), and predate disease. The oral pathogen Porphyromonas gingivalis may play a …

Objective Anti–citrullinated protein antibodies (ACPAs) display high association with rheumatoid
arthritis (RA) and are implicated in its pathogenesis. The presence of ACPAs is known …

Objective. The aim of this study was to compare oral abnormalities and oral health-related
quality of life (HRQoL) of patients with SSc with the general population. Methods. SSc patients …

Objective. To determine the prevalence of anti-cyclic citrullinated peptide (anti-CCP) antibodies
in unaffected relatives of North American Native probands with rheumatoid arthritis (RA); …

Objective Systemic sclerosis (SSc; scleroderma) is associated with decreased saliva production
and interincisal distance, more missing teeth, and periodontal disease. We undertook …

Objective The aim of this study was to compare oral radiologic abnormalities associated
with systemic sclerosis (SSc) against abnormalities in the general population. Study Design …

Objective The goal of this study was to determine the sensitivity of the new 2013 classification
criteria for systemic sclerosis (SSc; scleroderma) in an independent cohort of SSc subjects …

Aim: Up to 50% of patients with systemic sclerosis (SSc) have complaints of dyspnoea. We
evaluated the independent contributions of dyspnoea to function and health related quality of …