Background and aims The interferon-induced transmembrane proteins play an important
antiviral role by preventing viruses from traversing the cellular lipid bilayer. IFITM3 gene …

Objective The killer cell immunoglobulin‐like receptors (KIRs) form a group of regulatory
molecules that specifically recognize HLA class I molecules. The aim of this study was to …

Killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) loci are
both highly polymorphic. The aim of this study was to perform a KIR genotype analysis and …

Acute myeloid leukemia (AML) is a disease with great morphological and genetic heterogeneity,
which complicates its prognosis and treatment. The hypomethylating agents azacitidine …

In recent years, the macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage
CSF (GM-CSF) cytokines have been identified as opposing regulators of the …

The aim of this study was to analyse the association of specific killer cell immunoglobulin-like
receptors (KIR) genes and haplotypes with susceptibility to ankylosing spondylitis (AS) and …

The aim of this study was to identify new genetic variants associated with the severity of
ankylosing spondylitis (AS). We sequenced the exome of eight patients diagnosed with AS, …

Background: Variants in IFIH1, a gene coding the cytoplasmatic RNA sensor MDA5, regulate
the response to viral infections. We hypothesized that IFIH1 rs199076 variants would …

BACKGROUND & AIMS: The advent of new chronic hepatitis C virus (HCV) therapies
requires characterization of patients in order to predict adequate treatment. A good candidate …

We aimed to analyze the possible association of KIR/HLA-C genotypes with the susceptibility
to Crohn’s disease (CD) in a Spanish population. A total of 125 patients with CD and 339 …