A randomized placebo-controlled trial of methotrexate in psoriatic arthritis
…, A Kowalczyk, H Taylor, F Ibrahim, JC Packham… - …, 2012 - academic.oup.com
Objective. MTX is widely used to treat synovitis in PsA without supporting trial evidence. The
aim of our study was to test the value of MTX in the first large randomized placebo-…
aim of our study was to test the value of MTX in the first large randomized placebo-…
Impact of ankylosing spondylitis on work in patients across the UK
…, KP Jordan, A Garratt, JC Packham - Scandinavian journal …, 2011 - Taylor & Francis
Objectives: To examine the impact of ankylosing spondylitis (AS) on patients across the UK
and to identify factors associated with unemployment, absenteeism, and presenteeism. …
and to identify factors associated with unemployment, absenteeism, and presenteeism. …
[HTML][HTML] Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis
DL Mattey, JC Packham, NB Nixon, L Coates… - Arthritis research & …, 2012 - Springer
Introduction The pathology of ankylosing spondylitis (AS) suggests that certain cytokines and
matrix metalloproteinases (MMPs) might provide useful markers of disease activity. Serum …
matrix metalloproteinases (MMPs) might provide useful markers of disease activity. Serum …
Relationship between smoking and patient-reported measures of disease outcome in ankylosing spondylitis
…, SR Dawson, EL Healey, JC Packham - The Journal of …, 2011 - jrheum.org
Objective. To investigate the relationship between smoking and disease activity, pain, function,
and quality of life in patients with ankylosing spondylitis (AS). Methods. Patients with AS (…
and quality of life in patients with ankylosing spondylitis (AS). Methods. Patients with AS (…
Increased risk of hypertension associated with spondyloarthritis disease duration: results from the ASAS-COMOSPA study
Objective. Spondyloarthritis (SpA) is associated with a number of cardiovascular (CV)
comorbidities. We examined the association of SpA disease duration and delay in diagnosis with …
comorbidities. We examined the association of SpA disease duration and delay in diagnosis with …
Effect of psychological distress on continuation of anti-tumor necrosis factor therapy in patients with rheumatoid arthritis
…, AB Hassell, A Brownfield, JC Packham - The Journal of …, 2010 - jrheum.org
Objective. To investigate the relationship of psychological distress and associated factors with
continuation of tumor necrosis factor (TNF) antagonist therapy in patients with rheumatoid …
continuation of tumor necrosis factor (TNF) antagonist therapy in patients with rheumatoid …
Interaction between smoking and polymorphism in the promoter region of the VEGFA gene is associated with ischemic heart disease and myocardial infarction in …
Y Chen, PT Dawes, JC Packham… - The Journal of …, 2011 - jrheum.org
Objective. To determine whether variants in the vascular endothelial growth factor A (VEGFA)
gene are associated with ischemic heart disease (IHD) and/or myocardial infarction (MI) in …
gene are associated with ischemic heart disease (IHD) and/or myocardial infarction (MI) in …
Assessing fatigue in ankylosing spondylitis: the importance of frequency and severity
KL Haywood, JC Packham, KP Jordan - Rheumatology, 2014 - academic.oup.com
Objective. The aim of this study was to explore the value of assessing fatigue frequency and
its relationship with fatigue severity in a UK cohort of AS patients. Methods. Single items …
its relationship with fatigue severity in a UK cohort of AS patients. Methods. Single items …
Evaluation of ankylosing spondylitis quality of life (EASi-QoL): reliability and validity of a new patient-reported outcome measure
…, KP Jordan, EL Healey, JC Packham - The Journal of …, 2010 - jrheum.org
Objective. There is currently no universally accepted measure of quality of life in ankylosing
spondylitis (AS). Our objective was to develop and evaluate a patient-reported outcome …
spondylitis (AS). Our objective was to develop and evaluate a patient-reported outcome …
Qualitative interview study exploring the patient experience of living with axial spondyloarthritis and fatigue: difficult, demanding and draining
…, G Strickland, J Thompson, JC Packham… - BMJ open, 2022 - bmjopen.bmj.com
Objective To explore patients’ lived experiences of axial spondyloarthritis (axSpA) and
fatigue. Design Interpretative phenomenological analysis (lived experience) was used as the …
fatigue. Design Interpretative phenomenological analysis (lived experience) was used as the …