Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and
ethnic disparities. We report a large transancestral association study of SLE using Immunochip …

Background. Polyclonal antithymocyte globulin (ATG) is widely used as an anti–T-cell agent
for induction and treatment of acute cellular rejection in solid organ transplantation. The …

Unmethylated CpG DNA activation of naive CD27 − B cells has been reported to require B-cell–receptor
(BCR) cross-linking. We describe a culture system using CpG DNA with …

Objective Systemic juvenile idiopathic arthritis (JIA) is associated with a recently recognized,
albeit poorly defined and characterized, lung disease (LD). The objective of this study was …

Objective. In a cohort of 70 patients with childhood-onset systemic lupus erythematosus (cSLE):
to determine the baseline adherence to medications and visits; to investigate the effects …

… John Looney MD (Professor of Medicine) , Jennifer Huggins MD (Fellow) …

Systemic lupus erythematosus (SLE) results from complex abnormalities of the innate and
acquired immune systems. For reasons that are currently not well understood, the disease …

Current monoclonal antibody therapies for multiple myeloma have had limited success,
perhaps due to narrow target specificity. We have previously described the ability of polyclonal …

Two patients presented at the University of Rochester Medical Center with a febrile illness,
cytopenias, organ failure (liver failure or respiratory failure), and markedly elevated serum …

Objective To obtain international consensus around processes that support the delivery of
high‐quality care to patients with childhood‐onset systemic lupus erythematosus (SLE) based …