ANCA are detectable in nearly all patients with active severe Wegener's granulomatosis

JD Finkielman, AS Lee, AM Hummel, MA Viss… - The American journal of …, 2007 - Elsevier
BACKGROUND: The pathogenic significance of antineutrophilic cytoplasmic antibodies (ANCA)
in Wegener’s granulomatosis is controversial. Their presence is influenced by the extent…

Antiproteinase 3 antineutrophil cytoplasmic antibodies and disease activity in Wegener granulomatosis

JD Finkielman, PA Merkel, D Schroeder… - Annals of internal …, 2007 - acpjournals.org
Background: The utility of antineutrophil cytoplasmic antibody (ANCA) levels to guide the
management of patients with Wegener granulomatosis remains controversial. Objective: To …

The hospital mortality of patients admitted to the ICU on weekends

…, IJ Morales, SG Peters, MT Keegan, JD Finkielman… - Chest, 2004 - Elsevier
Study objectives: Previous studies have suggested that patients are more likely to die in the
hospital if they are admitted on a weekend than on a weekday. This study was conducted to …

Mortality rate and length of stay of patients admitted to the intensive care unit in July

JD Finkielman, IJ Morales, SG Peters… - Critical care …, 2004 - journals.lww.com
Objective: At the beginning of each academic year in July, inexperienced residents and fellows
begin to care for patients. This inexperience can lead to poor patient outcome, especially …

[HTML][HTML] The incidence of relative adrenal insufficiency in patients with septic shock after the administration of etomidate

Z Mohammad, B Afessa, JD Finkielman - Critical Care, 2006 - Springer
Introduction Etomidate blocks adrenocortical synthesis when it is administered intravenously
as a continuous infusion or a single bolus. The influence of etomidate administration on the …

[HTML][HTML] Underweight is independently associated with mortality in post-operative and non-operative patients admitted to the intensive care unit: a retrospective study

JD Finkielman, O Gajic, B Afessa - BMC emergency medicine, 2004 - Springer
Background Low and high body mass index (BMI) have been recently shown to be associated
with increased and decreased mortality after ICU admission, respectively. The objective of …

Functional characterization of antineutrophil cytoplasmic antibodies in patients with cocaine‐induced midline destructive lesions

T Peikert, JD Finkielman, AM Hummel… - Arthritis & …, 2008 - Wiley Online Library
Objective Antineutrophil cytoplasmic antibodies (ANCA) binding to neutrophil elastase (NE)
and proteinase 3 (PR3) are detectable in most patients with cocaine‐induced midline …

Identifying potentially ineffective care in the sickest critically ill patients on the third ICU day

B Afessa, MT Keegan, Z Mohammad, JD Finkielman… - Chest, 2004 - Elsevier
Objective: To determine if an increase in the third-ICU-day acute physiology score (APS) of
the APACHE (acute physiology and chronic health evaluation) III prognostic system can …

Relationship between markers of platelet activation and inflammation with disease activity in Wegener's granulomatosis

…, M Lavalley, K Tanriverdi, JD Finkielman… - The Journal of …, 2011 - jrheum.org
Objective. There remains a need for biomarkers to guide therapy in antineutrophil cytoplasmic
antibody (ANCA)-associated vasculitis. Our objective was to determine whether measures …

[HTML][HTML] The initial Mayo Clinic experience using high-frequency oscillatory ventilation for adult patients: a retrospective study

JD Finkielman, O Gajic, JC Farmer, B Afessa… - BMC Emergency …, 2006 - Springer
Background High-frequency oscillatory ventilation (HFOV) was introduced in our institution
in June 2003. Since then, there has been no protocol to guide the use of HFOV, and all …