Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

Triceps splitting, triceps reflecting, and olecranon osteotomy are the most common posterior
surgical approaches to the adult elbow, but no comparative data exist as to the exposure …

Extraction of bone contours from radiographs plays an important role in disease diagnosis,
preoperative planning, and treatment analysis. We present a fully automatic method to …

The aim of this study was to assess the diagnostic accuracy of radiology department–based
hip aspiration for the diagnosis of infection after total hip arthroplasty. Patient selection …

Objectives Osteoarthritis (OA) is the most prevalent form of arthritis and accounts for substantial
morbidity and disability, particularly in older people. It is characterised by changes in …

Osteoarthritis (OA) is a prevalent, heritable degenerative joint disease with a substantial
public health impact. We used a 1000-Genomes-Project-based imputation in a genome-wide …

Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component.
To identify novel loci associated with hip OA we performed a meta-analysis of genome…

Purpose: Breast cancer bone metastases are incurable, highlighting the need for new
therapeutic targets. After colonizing bone, breast cancer cells remain dormant, until signals from …

Objective To assess candidate genes for association with osteoarthritis (OA) and identify
promising genetic factors and, secondarily, to assess the candidate gene approach in OA. …

Metal-on-metal hip replacement (MOMHR) using large diameter bearings has become a
popular alternative to conventional total hip arthroplasty, but is associated with elevated local …