Predictive value of antinuclear autoantibodies: the lessons of the systemic sclerosis autoantibodies

M Koenig, M Dieudé, JL Senécal - Autoimmunity reviews, 2008 - Elsevier
Physicians who provide care to patients with systemic sclerosis (SSc, scleroderma) ask
themselves several questions: Is SSc the correct diagnosis? Can the disease course be predicted…

[HTML][HTML] Scleromyositis: a distinct novel entity within the systemic sclerosis and autoimmune myositis spectrum. Implications for care and pathogenesis

…, Y Troyanov, M Hudson, JL Senécal… - Frontiers in …, 2023 - frontiersin.org
Systemic sclerosis and autoimmune myositis are both associated with decreased quality of
life and increased mortality. Their prognosis and management largely depend on the disease …

Histopathological features of systemic sclerosis-associated myopathy: a scoping review

…, J Bourré-Tessier, M Satoh, MJ Fritzler, JL Senécal… - Autoimmunity …, 2021 - Elsevier
Background Scleromyositis (SM) is an emerging subset of myositis associated with features
of systemic sclerosis (SSc) but it is currently not recognized as a distinct histopathological …

Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus

…, PR Fortin, AE Clarke, JL Senécal - Arthritis & …, 2001 - Wiley Online Library
Objective The frequency of coronary heart disease (CHD) and stroke are increased in
systemic lupus erythematosus (SLE), but the extent of the increase is uncertain. We sought to …

Novel classification of idiopathic inflammatory myopathies based on overlap syndrome features and autoantibodies: analysis of 100 French Canadian patients

…, JL Tremblay, JR Goulet, Y Raymond, JL Senécal - Medicine, 2005 - journals.lww.com
Our objective was to improve the currently imperfect classifications of idiopathic inflammatory
myopathies (IIM). In clinical practice, overlap features are common in IIM. This provided a …

Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty‐year …

…, T Grodzicky, Y Raymond, JL Senécal - … : Official Journal of …, 2008 - Wiley Online Library
Objective To identify in patients with Raynaud's phenomenon (RP) independent markers
that predict progression to definite systemic sclerosis (SSc) and to determine in patients with …

Predicting mortality in systemic sclerosis: analysis of a cohort of 309 French Canadian patients with emphasis on features at diagnosis as predictive factors for survival

…, E Rich, JR Goulet, Y Raymond, JL Senécal - Medicine, 2002 - journals.lww.com
Systemic sclerosis (SSc), or scleroderma, is a systemic autoimmune disease characterized
by microvascular involvement, fibroblast activation and excessive production of collagen with …

[HTML][HTML] Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes

…, MJ Fritzler, IN Targoff, Y Troyanov, JL Senécal - Arthritis research & …, 2007 - Springer
The objective of this study was to determine the prevalence, mutual associations, clinical
manifestations, and diagnoses associated with serum autoantibodies, as detected using …

DNA topoisomerase I binding to fibroblasts induces monocyte adhesion and activation in the presence of anti–topoisomerase I autoantibodies from systemic sclerosis …

J Hénault, G Robitaille, JL Senécal… - Arthritis & …, 2006 - Wiley Online Library
Objective Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis due
to excessive and dysregulated collagen production by fibroblasts. Previously, we reported …

Treatment algorithms in systemic lupus erythematosus

…, PT Nash, RA Furie, JL Senécal… - Arthritis care & …, 2015 - Wiley Online Library
Objective To establish agreement on systemic lupus erythematosus (SLE) treatment.
Methods SLE experts (n = 69) were e‐mailed scenarios and indicated preferred treatments. …