Background—The accumulation of macrophage-derived foam cells in atherosclerotic
lesions correlates with increased local release of matrix-degrading metalloproteinases (MMPs) …

HIV-positive individuals are at increased risk for kidney disease, including HIV-associated
nephropathy, noncollapsing focal segmental glomerulosclerosis, immune-complex kidney …

Background and objectives: Standard treatment for lupus nephritis, including corticosteroids
and cyclophosphamide, is efficient but is still associated with refractory or relapsing disease, …

Thrombotic microangiopathy (TMA) is a microvascular occlusive disorder characterized by
predominantly platelet thrombi in the renal and/or systemic circulations. Haemolytic uraemic …

OBJECTIVES: We characterized the transcriptional profiles of GM-CSF- (GM-MØ) and M-CSF-induced
macrophages (M-MØ) and investigated in situ a subset of differentially expressed …

Objective Expanded clinical experience with patients treated by pembrolizumab has accumulated.
However, renal toxicities associated with this anti-programmed cell death 1 agent are …

Hepatitis C virus (HCV) infection represents, by far, the major cause of mixed cryoglobulinemia
(MC). The renal disease associated with this pathological condition is now well described…

Background Pregnancy-related renal cortical necrosis may lead to end-stage renal disease.
Although this obstetric complication had virtually disappeared in high-income countries, we …

In rodents, parietal epithelial cells (PECs) migrating onto the glomerular tuft participate in the
formation of focal segmental glomerulosclerosis (FSGS) lesions. We investigated whether …

Background. Treatment and co-morbidities of human immunodeficiency virus (HIV)-infected
individuals have changed dramatically in the last 20 years with a potential impact on renal …