Background A substantial number of patients with rheumatoid arthritis have an inadequate
or unsustained response to tumor necrosis factor α (TNF-α) inhibitors. We conducted a …

Background Effective new therapies are needed for rheumatoid arthritis. Current therapies
target the products of activated macrophages; however, T cells also have an important role in …

Objective To determine the clinical efficacy, safety, and immunogenicity of abatacept (CTLA‐4Ig),
a selective costimulation modulator, in patients with rheumatoid arthritis (RA) that has …

Objective T cells are involved in the pathogenesis of rheumatoid arthritis (RA). In animal
models of autoimmune diseases, blockade of costimulatory molecules on antigen‐presenting …

Importance Treatment nonadherence and relapse are common problems in patients with
schizophrenia. The long-acting 3-month formulation of paliperidone palmitate, owing to its …

The clinical management of 746 eyes in 417 patients referred for keratoconus from January
1984 through January 1988 was retrospectively analyzed. In 357 patients, 554 eyes (74%) …

Objective: To evaluate the efficacy and safety of an extended-release (ER) formulation of
paliperidone in patients with an acute episode of schizophrenia, in the dosage range of 3 to 15 …

Background: This double-blind, parallel-group, multicenter, phase-3 study was designed to
test the noninferiority of paliperidone palmitate 3-month formulation (PP3M) to the currently …

OBJECTIVES: A randomized controlled trial evaluated the impact of feedback and financial
incentives on physician compliance with cancer screening guidelines for women 50 years of …

Recent trends in health care have placed increased burden on cancer caregivers. In response,
nurses and social workers were taught to implement a 6-hour psychoeducational Family …