• Six hundred sixty-two consecutive patients with acetaminophen overdoses were evaluated.
Those at risk on the basis of their acetaminophen blood levels, as plotted on the study …

Abstract Analysis of covariance is an effective method for addressing two considerations for
randomized clinical trials. One is reduction of variance for estimates of treatment effects and …

Many studies in the pharmaceutical sciences are concerned with the relationships between
categorical response variables which describe favorable or unfavorable outcome and one or …

Thirty-one men with androgenetic alopecia completed 4½ to 5 years of therapy with 2% and
3% topical minoxidil. Hair regrowth with topical minoxidil tended to peak at 1 year with a …

Three general methods for covariance analysis of categorical data are reviewed and applied
to an example from a clinical trial in rheumatoid arthritis. The three methods considered are …

We examined the natural history of mitral-valve prolapse in 53 patients who had had a
midsystolic click or late systolic murmur (or both) documented phonocardiographically a mean of …

OBJECTIVE: To estimate relative efficiencies of the 7 rheumatoid arthritis (RA) Core Data Set
measures to distinguish adalimumab from control treatments in 4 clinical trials. METHODS: …

OBJECTIVE: To analyze 2 indices composed of the 3 patient reported outcomes (PRO) in
the American College of Rheumatology (ACR) Core Data Set--physical function, pain, and …

In order to better understand the electrophysiology of the diseased human atrium, we
measured high right atrial refractory periods, threshold, and conduction times of 61 patients …

Objective: To carry out a meta-analysis designed to compare the discriminant capacities of
American College of Rheumatology 50% (ACR50) with 20% (ACR20) responses in clinical …