The aim was to update the 2009 European League against Rheumatism (EULAR)
recommendations for the treatment of systemic sclerosis (SSc), with attention to new therapeutic …

Background Tumor necrosis factor (TNF) has a pathogenic role in juvenile rheumatoid
arthritis. We evaluated the efficacy and safety of adalimumab, a fully human monoclonal anti-TNF …

Objective To determine the clinical and immunologic features of systemic sclerosis (SSc) in
a large group of children and describe the clinical evolution of the disease and compare it …

Objective. Juvenile localized scleroderma (JLS) includes a number of conditions often grouped
together. With the long-term goal of developing uniform classification criteria, we studied …

Objective: To describe a registry set up to monitor children treated with etanercept in Germany
and Austria. Methods: Giannini’s criteria, duration of morning stiffness, number of swollen, …

The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a
primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). …

Context Novel therapies have improved the remission rate in chronic inflammatory disorders
including juvenile idiopathic arthritis (JIA). Therefore, strategies of tapering therapy and …

Background Systemic sclerosis-associated interstitial lung disease (ILD) carries a high
mortality risk; expert guidance is required to aid early recognition and treatment. We aimed to …

Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology
of the microcirculation. Since its recent incorporation in the 2013 American College of …

Objective We previously documented that abatacept was effective and safe in patients with
juvenile idiopathic arthritis (JIA) who had not previously achieved a satisfactory clinical …